Képes-e a jobb kamra hosszú távon biztosítani a szisztémás keringést? Nagyér-transzpozíciós betegeken végzett Senning-mutétek késoi eredményei

Translated title of the contribution: Is the right ventricle able to maintain the systemic circulation for a long time? The late results of the Senning operation for complete transposition of the great arteries

István Hartyánszky, Krisztina Kádár, Valéria Oprea, Károly Lozsádi, Judit Szabolcs, András Szatmári

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The successful surgical management of congenital heart defects increased the number of such a type of defects, in which the morfological right venticle has to provide the systemic circulation. Children with transposition of the great arteries operated with Senning procedure are good examples to investigate the long-term right ventricular function. Aim of our study was to determine the adequate noninvazive methods to assess the progression of the right ventricular diszfunkción, to analyse the long-term surgical results and to determine the indication of reoperation. Methods: Physical examination, electrocardiogram, 24 hours ECG, stresstesting, echocardiography, B-natriuretic peptid level measurement and magnetic resonance imagine were performed. Patients: 176 Senning operations were carried out between 1980 and 1997. The follow-up period was 9-25 (mean 12.5) years and 83 children were included in our study. Results: Significant correlations were found between the MRI RVEF, and echocardiographic TEI index, TDI and BNP results. Abnormal values were found in Senning patients compared to healthy children in MRI RVEF 55%, echocardiographic TEI index 0.33, in RV TDI systolic velocities 0.2 m/s, and B-natriuretic peptid levels 150 pg/ml. That means that right ventricular disfunction is expected in Senning children even without clinical symptoms. Conclusions: 1. BNP and echocardiographic TEI and TDI became available methods for the follow-up of right ventricular disfunction, and annual MRI is recommended. 2. Conversion of Senning to anatomic repair is considerable in selected young patients because the capacity of myocardium to respond to pressure overload decreasing with age. In older children and adults very close follow-up is necessary using biomarkers, echocardiography and MRI to decide the correct time of heart transplantation.

Translated title of the contributionIs the right ventricle able to maintain the systemic circulation for a long time? The late results of the Senning operation for complete transposition of the great arteries
Original languageHungarian
Pages (from-to)2155-2160
Number of pages6
JournalOrvosi hetilap
Volume147
Issue number45
Publication statusPublished - Nov 12 2006

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Is the right ventricle able to maintain the systemic circulation for a long time? The late results of the Senning operation for complete transposition of the great arteries'. Together they form a unique fingerprint.

  • Cite this