Is ADHD severity in adults associated with the lifetime prevalence of comorbid depressive episodes and anxiety disorders?

V. Simon, P. Czobor, I. Bitter

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Purpose: The objective of the present study was to examine the association between ADHD severity and the lifetime prevalence of comorbid depressive episodes and anxiety disorders in adults with ADHD. Subjects/materials and methods: Analyses were based on data of the Conner's Adult ADHD Rating Scale (CAARS) and a parent study examining the epidemiology of adult ADHD in 17 GP practices in Budapest, Hungary. Subjects between 18 and 60 years were included in the screening phase (n= 3529). Out of 279 positively screened subjects 161 participated in a clinical interview and completed the CAARS to confirm the diagnosis. We applied four diagnostic criteria: "DSM-IV"; "No-onset" (DSM-IV criteria without the specific requirement for onset); "Symptoms-only" (DSM-IV symptom criterion only); and "Reduced symptoms-only" (DSM-IV symptom criterion with a reduced threshold for symptom count). The MINI PLUS 5.0 was used to assess psychiatric comorbidity. Results: ADHD severity, as measured by the CAARS ADHD Index, showed a significant positive association with the prevalence of comorbid depressive episodes in all but the "ADHD_No-onset" group (" DSM-IV": F[1.23] = 8.39, P= 0.0081; "No-onset": F(1.27) = 0.97, P= 0.3346; "Symptoms-only": F[1.55] = 30.79, P<0.0001; "Reduced symptoms-only": F(1.62) = 26.69, P<0.0001). Discussion and conclusion: Results indicate that ADHD symptom severity increases in association with lifetime comorbidity with depression.

Original languageEnglish
Pages (from-to)308-314
Number of pages7
JournalEuropean Psychiatry
Volume28
Issue number5
DOIs
Publication statusPublished - Jun 2013

Fingerprint

Depressive Disorder
Anxiety Disorders
Diagnostic and Statistical Manual of Mental Disorders
Comorbidity
Hungary
Psychiatry
Epidemiology
Interviews
Depression

Keywords

  • Adult ADHD
  • Anxiety
  • CAARS
  • Comorbidity
  • Depression
  • Severity

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

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title = "Is ADHD severity in adults associated with the lifetime prevalence of comorbid depressive episodes and anxiety disorders?",
abstract = "Purpose: The objective of the present study was to examine the association between ADHD severity and the lifetime prevalence of comorbid depressive episodes and anxiety disorders in adults with ADHD. Subjects/materials and methods: Analyses were based on data of the Conner's Adult ADHD Rating Scale (CAARS) and a parent study examining the epidemiology of adult ADHD in 17 GP practices in Budapest, Hungary. Subjects between 18 and 60 years were included in the screening phase (n= 3529). Out of 279 positively screened subjects 161 participated in a clinical interview and completed the CAARS to confirm the diagnosis. We applied four diagnostic criteria: {"}DSM-IV{"}; {"}No-onset{"} (DSM-IV criteria without the specific requirement for onset); {"}Symptoms-only{"} (DSM-IV symptom criterion only); and {"}Reduced symptoms-only{"} (DSM-IV symptom criterion with a reduced threshold for symptom count). The MINI PLUS 5.0 was used to assess psychiatric comorbidity. Results: ADHD severity, as measured by the CAARS ADHD Index, showed a significant positive association with the prevalence of comorbid depressive episodes in all but the {"}ADHD_No-onset{"} group ({"} DSM-IV{"}: F[1.23] = 8.39, P= 0.0081; {"}No-onset{"}: F(1.27) = 0.97, P= 0.3346; {"}Symptoms-only{"}: F[1.55] = 30.79, P<0.0001; {"}Reduced symptoms-only{"}: F(1.62) = 26.69, P<0.0001). Discussion and conclusion: Results indicate that ADHD symptom severity increases in association with lifetime comorbidity with depression.",
keywords = "Adult ADHD, Anxiety, CAARS, Comorbidity, Depression, Severity",
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N2 - Purpose: The objective of the present study was to examine the association between ADHD severity and the lifetime prevalence of comorbid depressive episodes and anxiety disorders in adults with ADHD. Subjects/materials and methods: Analyses were based on data of the Conner's Adult ADHD Rating Scale (CAARS) and a parent study examining the epidemiology of adult ADHD in 17 GP practices in Budapest, Hungary. Subjects between 18 and 60 years were included in the screening phase (n= 3529). Out of 279 positively screened subjects 161 participated in a clinical interview and completed the CAARS to confirm the diagnosis. We applied four diagnostic criteria: "DSM-IV"; "No-onset" (DSM-IV criteria without the specific requirement for onset); "Symptoms-only" (DSM-IV symptom criterion only); and "Reduced symptoms-only" (DSM-IV symptom criterion with a reduced threshold for symptom count). The MINI PLUS 5.0 was used to assess psychiatric comorbidity. Results: ADHD severity, as measured by the CAARS ADHD Index, showed a significant positive association with the prevalence of comorbid depressive episodes in all but the "ADHD_No-onset" group (" DSM-IV": F[1.23] = 8.39, P= 0.0081; "No-onset": F(1.27) = 0.97, P= 0.3346; "Symptoms-only": F[1.55] = 30.79, P<0.0001; "Reduced symptoms-only": F(1.62) = 26.69, P<0.0001). Discussion and conclusion: Results indicate that ADHD symptom severity increases in association with lifetime comorbidity with depression.

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