Is a failure to recognize an increase in food intake a key to understanding insulin-induced weight gain?

Miriam Ryan, M. Barbara E. Livingstone, Pierre Henri Ducluzeau, Agnès Sallé, Manon Genaitay, Patrick Ritz

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22 Citations (Scopus)


The present study aimed to assess the contribution of energy intake to positive energy balance and weight gain with insulin therapy. Changes in energy intake (self-report and weighed food intake), dietary behavior (auto-questionnaires), resting energy expenditure (REE) (indirect calorimetry), physical activity (accelerometry), and glucosuria were monitored over the first 6 months of insulin therapy in 46 diabetic adults. No change in REE, activity, or glucosuria could explain weight gain in the type 1 (4.1 ± 0.6 kg, P < 0.0001) or type 2 (1.8 ± 0.8 kg, P = 0.02) diabetic groups. An increase in energy intake provides the most likely explanation for weight gain with insulin. However, it is not being recognized because of significant underestimation of self-reported food intake, which appears to be associated with increased dietary restraint.

Original languageEnglish
Pages (from-to)448-450
Number of pages3
JournalDiabetes care
Issue number3
Publication statusPublished - Mar 2008


ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialised Nursing

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