Iris structure and minor physical anomalies in schizophrenia

Dániel Trixler, T. Tényi

Research output: Contribution to journalArticle

Abstract

This study compared five human iris characteristics and minor physical anomalies (MPAs) between patients with schizophrenia (n = 32) and controls (n = 31). Correlations between iris characteristics and MPAs were expected, due to their same ectodermic origin. Iris macro photos were taken and quantified in five categories mentioned before. MPAs were also examined in both groups. Our results show significant differences in the frequency of pigment dots of the iris and total number of MPAs between groups. Other significant differences were found in the extension of concentric furrows, as they were more common in healthy subjects, while Wolfflin nodules occurred significantly more often in patients with schizophrenia. Expected difference in Fuch's crypts could not be observed between groups. Light eye color was positively correlated to pigment dots and Wolfflin nodules, and negatively correlated with concentric furrows. Dark eye color showed positive correlation with concentric furrows, and negative correlation with pigment dots and concentric furrows. A gender effect could also been observed: male individuals showed moderate positive correlations between pigment dots and total MPAs frequency, while this couldn't be observed in the female group. Our findings suggest possible connections between iris characteristics and MPAs, where males are more prone to deviations.

Original languageEnglish
Pages (from-to)412-416
Number of pages5
JournalPsychiatry Research
Volume256
DOIs
Publication statusPublished - Oct 1 2017

Fingerprint

Iris
Schizophrenia
Eye Color
Healthy Volunteers
Light

Keywords

  • Biological markers
  • Iris
  • Iris structure
  • Minor physical anomalies
  • Phenotype
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Iris structure and minor physical anomalies in schizophrenia. / Trixler, Dániel; Tényi, T.

In: Psychiatry Research, Vol. 256, 01.10.2017, p. 412-416.

Research output: Contribution to journalArticle

@article{55aac3b7b0bf40f8b7ae3e33162d0004,
title = "Iris structure and minor physical anomalies in schizophrenia",
abstract = "This study compared five human iris characteristics and minor physical anomalies (MPAs) between patients with schizophrenia (n = 32) and controls (n = 31). Correlations between iris characteristics and MPAs were expected, due to their same ectodermic origin. Iris macro photos were taken and quantified in five categories mentioned before. MPAs were also examined in both groups. Our results show significant differences in the frequency of pigment dots of the iris and total number of MPAs between groups. Other significant differences were found in the extension of concentric furrows, as they were more common in healthy subjects, while Wolfflin nodules occurred significantly more often in patients with schizophrenia. Expected difference in Fuch's crypts could not be observed between groups. Light eye color was positively correlated to pigment dots and Wolfflin nodules, and negatively correlated with concentric furrows. Dark eye color showed positive correlation with concentric furrows, and negative correlation with pigment dots and concentric furrows. A gender effect could also been observed: male individuals showed moderate positive correlations between pigment dots and total MPAs frequency, while this couldn't be observed in the female group. Our findings suggest possible connections between iris characteristics and MPAs, where males are more prone to deviations.",
keywords = "Biological markers, Iris, Iris structure, Minor physical anomalies, Phenotype, Schizophrenia",
author = "D{\'a}niel Trixler and T. T{\'e}nyi",
year = "2017",
month = "10",
day = "1",
doi = "10.1016/j.psychres.2017.07.004",
language = "English",
volume = "256",
pages = "412--416",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Iris structure and minor physical anomalies in schizophrenia

AU - Trixler, Dániel

AU - Tényi, T.

PY - 2017/10/1

Y1 - 2017/10/1

N2 - This study compared five human iris characteristics and minor physical anomalies (MPAs) between patients with schizophrenia (n = 32) and controls (n = 31). Correlations between iris characteristics and MPAs were expected, due to their same ectodermic origin. Iris macro photos were taken and quantified in five categories mentioned before. MPAs were also examined in both groups. Our results show significant differences in the frequency of pigment dots of the iris and total number of MPAs between groups. Other significant differences were found in the extension of concentric furrows, as they were more common in healthy subjects, while Wolfflin nodules occurred significantly more often in patients with schizophrenia. Expected difference in Fuch's crypts could not be observed between groups. Light eye color was positively correlated to pigment dots and Wolfflin nodules, and negatively correlated with concentric furrows. Dark eye color showed positive correlation with concentric furrows, and negative correlation with pigment dots and concentric furrows. A gender effect could also been observed: male individuals showed moderate positive correlations between pigment dots and total MPAs frequency, while this couldn't be observed in the female group. Our findings suggest possible connections between iris characteristics and MPAs, where males are more prone to deviations.

AB - This study compared five human iris characteristics and minor physical anomalies (MPAs) between patients with schizophrenia (n = 32) and controls (n = 31). Correlations between iris characteristics and MPAs were expected, due to their same ectodermic origin. Iris macro photos were taken and quantified in five categories mentioned before. MPAs were also examined in both groups. Our results show significant differences in the frequency of pigment dots of the iris and total number of MPAs between groups. Other significant differences were found in the extension of concentric furrows, as they were more common in healthy subjects, while Wolfflin nodules occurred significantly more often in patients with schizophrenia. Expected difference in Fuch's crypts could not be observed between groups. Light eye color was positively correlated to pigment dots and Wolfflin nodules, and negatively correlated with concentric furrows. Dark eye color showed positive correlation with concentric furrows, and negative correlation with pigment dots and concentric furrows. A gender effect could also been observed: male individuals showed moderate positive correlations between pigment dots and total MPAs frequency, while this couldn't be observed in the female group. Our findings suggest possible connections between iris characteristics and MPAs, where males are more prone to deviations.

KW - Biological markers

KW - Iris

KW - Iris structure

KW - Minor physical anomalies

KW - Phenotype

KW - Schizophrenia

UR - http://www.scopus.com/inward/record.url?scp=85021793566&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021793566&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2017.07.004

DO - 10.1016/j.psychres.2017.07.004

M3 - Article

VL - 256

SP - 412

EP - 416

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

ER -