Ionic currents in ventricular myocytes isolated from the heart of a patient with idiopathic cardiomyopathy

P. P. Nanasi, A. Varro, D. A. Lathrop

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Whole-cell configuration of the patch-clamp technique was applied to record ionic currents from human ventricular myocytes isolated from a cardiac transplant patient with idiopathic cardiomyopathy. Inward calcium current, transient outward current, and inward rectifier potassium current were recorded, while no discernible delayed rectifier potassium current was observed. Thus the currents that underlie electrical activity in human ventricular myocytes appear to resemble those reported earlier in canine and rabbit ventricular myocytes.

Original languageEnglish
Pages (from-to)85-89
Number of pages5
JournalCardioscience
Volume3
Issue number2
Publication statusPublished - Jan 1 1992

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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