Ion-Selective Electrodes Based on Hydrophilic Ionophore-Modified Nanopores

Soma Papp, Gyula Jágerszki, Róbert E. Gyurcsányi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We report the synthesis and analytical application of the first Cu2+-selective synthetic ion channel based on peptide-modified gold nanopores. A Cu2+-binding peptide motif (Gly-Gly-His) along with two additional functional thiol derivatives inferring cation-permselectivity and hydrophobicity was self-assembled on the surface of gold nanoporous membranes comprising of about 5 nm diameter pores. These membranes were used to construct ion-selective electrodes (ISEs) with extraordinary Cu2+ selectivities, approaching six orders of magnitude over certain ions. Since all constituents are immobilized to a supporting nanoporous membrane, their leaching, that is a ubiquitous problem of conventional ionophore-based ISEs was effectively suppressed.

Original languageEnglish
Pages (from-to)4752-4755
Number of pages4
JournalAngewandte Chemie - International Edition
Volume57
Issue number17
DOIs
Publication statusPublished - Apr 16 2018

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Keywords

  • copper-binding peptides
  • ion channels
  • ion-selective nanopores
  • self-assembled monolayers
  • sensors

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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