Iodine-125 brachytherapy of brain stem tumors

Jenö Julow, Árpád Viola, Tibor Major, István Valálik, Sarolta Sági, László Mangel, Beáta R. Kovács, Imre Repa, Gábor Bajzik, Takácsi N. Zoltán, György Németh

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: To report on iodine-125 (125I) interstitial irradiation in the treatment of brain stem tumors. Patients and Methods: Two patients with brain stem tumors were treated with CT- and image fusion-guided 125I stereotactic brachytherapy. Results: By March 2003, the patients had been followed up for 47 and 13 months, respectively. In case 1, the tumor volume was 1.98 cm3 on the control CT, indicating a 65.5% shrinkage as compared to a target volume of 5.73 cm3 at the time of brachytherapy. In case 2, shrinkage was more distinct. After irradiation, the cyst volume was 0.16 cm3 on the control MRI, indicating a 97.4% shrinkage as compared to a target volume of 6.05 cm3 at the time of brachytherapy, i.e., the metastasis had virtually disappeared. Conclusion: CT- and image fusion-guided 125I stereotactic brachytherapy can be performed during the biopsy session. The procedure can be well planned dosimetrically and is surgically precise.

Original languageEnglish
Pages (from-to)449-454
Number of pages6
JournalStrahlentherapie und Onkologie
Volume180
Issue number7
DOIs
Publication statusPublished - Jul 2004

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Brain Stem Neoplasms
Brachytherapy
Iodine
Tumor Burden
Cysts
Neoplasm Metastasis
Biopsy

Keywords

  • I interstitial irradiation
  • Brachytherapy
  • Brain stem glioma
  • Brain stem tumors
  • Image fusion
  • Tumor shrinkage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cancer Research
  • Radiological and Ultrasound Technology

Cite this

Julow, J., Viola, Á., Major, T., Valálik, I., Sági, S., Mangel, L., ... Németh, G. (2004). Iodine-125 brachytherapy of brain stem tumors. Strahlentherapie und Onkologie, 180(7), 449-454. https://doi.org/10.1007/s00066-004-1228-z

Iodine-125 brachytherapy of brain stem tumors. / Julow, Jenö; Viola, Árpád; Major, Tibor; Valálik, István; Sági, Sarolta; Mangel, László; Kovács, Beáta R.; Repa, Imre; Bajzik, Gábor; Zoltán, Takácsi N.; Németh, György.

In: Strahlentherapie und Onkologie, Vol. 180, No. 7, 07.2004, p. 449-454.

Research output: Contribution to journalArticle

Julow, J, Viola, Á, Major, T, Valálik, I, Sági, S, Mangel, L, Kovács, BR, Repa, I, Bajzik, G, Zoltán, TN & Németh, G 2004, 'Iodine-125 brachytherapy of brain stem tumors', Strahlentherapie und Onkologie, vol. 180, no. 7, pp. 449-454. https://doi.org/10.1007/s00066-004-1228-z
Julow J, Viola Á, Major T, Valálik I, Sági S, Mangel L et al. Iodine-125 brachytherapy of brain stem tumors. Strahlentherapie und Onkologie. 2004 Jul;180(7):449-454. https://doi.org/10.1007/s00066-004-1228-z
Julow, Jenö ; Viola, Árpád ; Major, Tibor ; Valálik, István ; Sági, Sarolta ; Mangel, László ; Kovács, Beáta R. ; Repa, Imre ; Bajzik, Gábor ; Zoltán, Takácsi N. ; Németh, György. / Iodine-125 brachytherapy of brain stem tumors. In: Strahlentherapie und Onkologie. 2004 ; Vol. 180, No. 7. pp. 449-454.
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