Iodine-125 brachytherapy of brain stem tumors

Jenö Julow, Árpád Viola, Tibor Major, István Valálik, Sarolta Sági, László Mangel, Beáta R. Kovács, Imre Repa, Gábor Bajzik, Takácsi N. Zoltán, György Németh

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Abstract

Purpose: To report on iodine-125 (125I) interstitial irradiation in the treatment of brain stem tumors. Patients and Methods: Two patients with brain stem tumors were treated with CT- and image fusion-guided 125I stereotactic brachytherapy. Results: By March 2003, the patients had been followed up for 47 and 13 months, respectively. In case 1, the tumor volume was 1.98 cm3 on the control CT, indicating a 65.5% shrinkage as compared to a target volume of 5.73 cm3 at the time of brachytherapy. In case 2, shrinkage was more distinct. After irradiation, the cyst volume was 0.16 cm3 on the control MRI, indicating a 97.4% shrinkage as compared to a target volume of 6.05 cm3 at the time of brachytherapy, i.e., the metastasis had virtually disappeared. Conclusion: CT- and image fusion-guided 125I stereotactic brachytherapy can be performed during the biopsy session. The procedure can be well planned dosimetrically and is surgically precise.

Original languageEnglish
Pages (from-to)449-454
Number of pages6
JournalStrahlentherapie und Onkologie
Volume180
Issue number7
DOIs
Publication statusPublished - Jul 1 2004

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Keywords

  • Brachytherapy
  • Brain stem glioma
  • Brain stem tumors
  • I interstitial irradiation
  • Image fusion
  • Tumor shrinkage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Oncology

Cite this

Julow, J., Viola, Á., Major, T., Valálik, I., Sági, S., Mangel, L., Kovács, B. R., Repa, I., Bajzik, G., Zoltán, T. N., & Németh, G. (2004). Iodine-125 brachytherapy of brain stem tumors. Strahlentherapie und Onkologie, 180(7), 449-454. https://doi.org/10.1007/s00066-004-1228-z