Hexagastrin, Arg 8-vasopressin, oxytocin, Tyr1-somatostatin, 1 and ACTH 1–39 were iodinated in order to yield precursors for tritium labelling or radioiodinated tracers for radioimmunoassay, respectively. The heterogeneous mixture of iodination products was purified via reversed-phase high-performance liquid chromatography. Iodination of peptides resulted in a marked increase in retention time on the reversed-phase adsorbent. A simple and quick method was applied for purification of radio-iodinated peptides on a Sep-pak R C-18 cartridge for rapid sample preparation.
ASJC Scopus subject areas
- Molecular Medicine