Investigations of the serum level of pregnancy associated alpha2 globulin during contraceptive treatment by means of radial immunodiffusion method

G. Than, I. F. Csaba, N. J. Karg, D. G. Szabo

Research output: Contribution to journalArticle

Abstract

The serum level of pregnancy associated alpha2 globulin was studied in 70 healthy women taking 3 different types of oral contraceptives [40 Bisecurin: containing 1.0 mg of Ethynodiol diaceticum +0.05 mg Ethynilestradiol; 20 Infecundin: containing 2.5 mg of Norethynodrel +0.1 mg of Mestranol; 10 Cervicundin: containing 0.5 mg of Ethynodiol disceticum]. Elevated amounts of serum level of pregnancy associated alpha2 globulin could be detected in 37 of the 40 women taking Bisecurin and in all 20 taking Infecundin. Cervicundin however, failed to induce any change in the serum protein pattern of the 10 subjects studied. Serum levels of pregnancy associated alpha2 globulin were higher in the Infecundin taking (53 mg%), than in the Bisecurin taking group (29 mg%). This shows the estrogen dependency of pregnancy associated alpha2 globulin and points to a possible implication of this globulin in the immunosuppressive processes.

Original languageEnglish
Pages (from-to)27-29
Number of pages3
JournalInternational Journal of Fertility
Volume20
Issue number1
Publication statusPublished - 1975

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Immunodiffusion
Globulins
Contraceptive Agents
Pregnancy
Serum
Norethynodrel
Mestranol
Therapeutics
Immunosuppressive Agents
Oral Contraceptives
Blood Proteins
Estrogens
Infecundin
Bisecurin I
ethynodiol

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Investigations of the serum level of pregnancy associated alpha2 globulin during contraceptive treatment by means of radial immunodiffusion method. / Than, G.; Csaba, I. F.; Karg, N. J.; Szabo, D. G.

In: International Journal of Fertility, Vol. 20, No. 1, 1975, p. 27-29.

Research output: Contribution to journalArticle

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