Investigation of the structure and properties of model membranes of the stratum corneum by small-angle neutron scattering

E. V. Zemlyanaya, M. A. Kiselev, R. Neubert, J. Kohlbrecher, V. Aksenov

Research output: Contribution to journalArticle

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Abstract

The structure and properties of a quaternary membrane based on ceramide 6 in unilamellar vesicles have been investigated using small-angle neutron scattering at temperatures of 32 and 60 °C. Calculations performed in the framework of the separated-form-factor method have demonstrated that the nanostructure of a bilayer formed by unilamellar vesicles in an excess of water differs from the nanostructure of a partially hydrated planar bilayer. The calculated neutron scattering spectrum in the range of small scattering angles deviates from the experimental neutron scattering spectrum. This difference between the calculated curve and the experimental spectrum suggests a strong short-range interaction of vesicles with each other and the formation of cluster structures, which confirms the occurrence of chain-flip transitions.

Original languageEnglish
Pages (from-to)884-889
Number of pages6
JournalSurface Investigation X-Ray, Synchrotron and Neutron Techniques
Volume2
Issue number6
DOIs
Publication statusPublished - Dec 2008

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Neutron scattering
Unilamellar Liposomes
Membranes
Nanostructures
Ceramides
Scattering
Water
Temperature

ASJC Scopus subject areas

  • Surfaces, Coatings and Films

Cite this

Investigation of the structure and properties of model membranes of the stratum corneum by small-angle neutron scattering. / Zemlyanaya, E. V.; Kiselev, M. A.; Neubert, R.; Kohlbrecher, J.; Aksenov, V.

In: Surface Investigation X-Ray, Synchrotron and Neutron Techniques, Vol. 2, No. 6, 12.2008, p. 884-889.

Research output: Contribution to journalArticle

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