Investigation of the effect of the ligand/palladium ratio on the catalytic activity of reusable palladium/phosphine/ionic liquid systems in aminocarbonylation of 17-iodo-androst-16-ene with amino acid ester nucleophiles

Eszter Takács, Rita Skoda-Földes

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Ionic liquids as solvents were used effectively in palladium catalysed aminocarbonylation of 17-iodo-5α- androst-16-ene (1) with L-amino acid esters. Interestingly, optimal conditions that are essential for the successful reuse of the ionic liquid/catalyst mixture differ greatly from those observed in the similar reaction with simple secondary amines as nucleophiles.

Original languageEnglish
Pages (from-to)448-452
Number of pages5
JournalLetters in Organic Chemistry
Volume6
Issue number6
DOIs
Publication statusPublished - Sep 1 2009

Keywords

  • Alkenyl iodide
  • Amino acid esters
  • Aminocarbonylation
  • Ionic liquids
  • Palladium

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Investigation of the effect of the ligand/palladium ratio on the catalytic activity of reusable palladium/phosphine/ionic liquid systems in aminocarbonylation of 17-iodo-androst-16-ene with amino acid ester nucleophiles'. Together they form a unique fingerprint.

  • Cite this