Investigation of the cyclodextrin complexes of mandelic acid derivatives

Cs Novák, A. Végh, S. Marokházi, G. Pokol, L. Szente

Research output: Contribution to journalArticle

4 Citations (Scopus)


Racemic free mandelic acid and its methyl, ethyl, isoamyl and benzyl esters were found to form inclusion complexes with all the three studied natural cyclodextrins proved by thermoanalytical results. Differences between the solid state stability of guests were detected mainly by evolved gas analysis. Even signs of an eventual optical resolution by molecular inclusion were observed in several cases, but still not sufficiently proven. Due to the rather high volatility and low melting points of the majority of guest substances DSC technique was found to be suitable for studying the cyclodextrin complexes of mandelic acid.

Original languageEnglish
Pages (from-to)181-190
Number of pages10
JournalJournal of thermal analysis
Issue number1
Publication statusPublished - Jan 1 1994


  • DSC
  • cyclodextrin complexes
  • mandelic acid derivatives

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Engineering(all)

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