Investigation of the chemical stability of a new growth hormone - Releasing hormone (GHRH)analogue by HPLC

M. Idei, I. Mezö, E. Z. Szabó, G. Kéri

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The stability of a new active growth hormone - releasing hormone analogue (D-Ala2Nle27, (gamma-amino-butyric acid)30-GHRH(1-30)-NH2) was investigated during storage at different temperatures in aqueous solution. Samples stored for various periods of time were analysed by HPLC. It is concluded that in aqueous solution D-Ala2,Nle27, (gamma-amino-butyric acid)30-growth hormone-releasing hormone (1-30)-NH2 is stable: at least for 36 days at 4°C; for 28 days at 25°C; and for 10 days at 37°C.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalBiomedical Chromatography
Volume10
Issue number2
Publication statusPublished - Mar 1996

Fingerprint

Growth Hormone-Releasing Hormone
Chemical stability
Butyric Acid
High Pressure Liquid Chromatography
Temperature

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Clinical Biochemistry
  • Analytical Chemistry
  • Pharmacology

Cite this

Investigation of the chemical stability of a new growth hormone - Releasing hormone (GHRH)analogue by HPLC. / Idei, M.; Mezö, I.; Szabó, E. Z.; Kéri, G.

In: Biomedical Chromatography, Vol. 10, No. 2, 03.1996, p. 89-91.

Research output: Contribution to journalArticle

@article{9f070af8d8004b25b41b82d31fdc2092,
title = "Investigation of the chemical stability of a new growth hormone - Releasing hormone (GHRH)analogue by HPLC",
abstract = "The stability of a new active growth hormone - releasing hormone analogue (D-Ala2Nle27, (gamma-amino-butyric acid)30-GHRH(1-30)-NH2) was investigated during storage at different temperatures in aqueous solution. Samples stored for various periods of time were analysed by HPLC. It is concluded that in aqueous solution D-Ala2,Nle27, (gamma-amino-butyric acid)30-growth hormone-releasing hormone (1-30)-NH2 is stable: at least for 36 days at 4°C; for 28 days at 25°C; and for 10 days at 37°C.",
author = "M. Idei and I. Mez{\"o} and Szab{\'o}, {E. Z.} and G. K{\'e}ri",
year = "1996",
month = "3",
language = "English",
volume = "10",
pages = "89--91",
journal = "Biomedical Chromatography",
issn = "0269-3879",
publisher = "John Wiley and Sons Ltd",
number = "2",

}

TY - JOUR

T1 - Investigation of the chemical stability of a new growth hormone - Releasing hormone (GHRH)analogue by HPLC

AU - Idei, M.

AU - Mezö, I.

AU - Szabó, E. Z.

AU - Kéri, G.

PY - 1996/3

Y1 - 1996/3

N2 - The stability of a new active growth hormone - releasing hormone analogue (D-Ala2Nle27, (gamma-amino-butyric acid)30-GHRH(1-30)-NH2) was investigated during storage at different temperatures in aqueous solution. Samples stored for various periods of time were analysed by HPLC. It is concluded that in aqueous solution D-Ala2,Nle27, (gamma-amino-butyric acid)30-growth hormone-releasing hormone (1-30)-NH2 is stable: at least for 36 days at 4°C; for 28 days at 25°C; and for 10 days at 37°C.

AB - The stability of a new active growth hormone - releasing hormone analogue (D-Ala2Nle27, (gamma-amino-butyric acid)30-GHRH(1-30)-NH2) was investigated during storage at different temperatures in aqueous solution. Samples stored for various periods of time were analysed by HPLC. It is concluded that in aqueous solution D-Ala2,Nle27, (gamma-amino-butyric acid)30-growth hormone-releasing hormone (1-30)-NH2 is stable: at least for 36 days at 4°C; for 28 days at 25°C; and for 10 days at 37°C.

UR - http://www.scopus.com/inward/record.url?scp=0029998689&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029998689&partnerID=8YFLogxK

M3 - Article

C2 - 8924733

AN - SCOPUS:0029998689

VL - 10

SP - 89

EP - 91

JO - Biomedical Chromatography

JF - Biomedical Chromatography

SN - 0269-3879

IS - 2

ER -