Six polymers with different structure were investigated. The polymers studied were as follows: methylcellulose, hydroxyethylcellulose, carboxymethylcellulose sodium, polyacrylate sodium-polyacrylamid copolymer (Hostacerin PN 73), poly(vinylpyrrolidone)-poly(vinylacetate) copolymer (Kollidon VA 64) and poly(ethylenoxide)-poly(propylenoxide) blockpolymer. Physical networks from polymers in aqueous media were prepared. The flow curves of these systems were determined. Polynoms, multiplicative functions and linear ones were fitted to the flow curves. The close packing was characterised by correlation coefficient. Physical content of function constants was delineated. Practically the constants expressing the binding forces has a great importance. It was established, that the binding forces in cellulose derivates gels and that of acrylic acid-acrylamide polymer gels are similar. Other structure binding forces act in the poly(ethylenoxide)-poly(propylenoxide) block-copolymer systems. The difference are well demonstrated by the constants values of functions.
|Number of pages||9|
|Journal||Acta pharmaceutica Hungarica|
|Publication status||Published - Oct 14 2005|
ASJC Scopus subject areas
- Pharmaceutical Science