Abstract
The toxic effects of the γ‐hexachlorocyclohexane metabolite γ‐pentachlorocyclohexene (γ‐PCCH) were studied by acute and subacute (6 weeks) experiments. The investigations included cerebral convulsibility with chemoshock (Tetrazolium), reactivity with hot plate method, the learning ability with learning tests, and peripheral nervous activity (EMG). Nociceptive reaction time was not influenced, the learning process (6 weeks) was inhibited by γ‐PCCH. The conduction velocity of the peripheral nerve was decreased. At the end of the 6th week liver enlargement was found.
| Original language | English |
|---|---|
| Pages (from-to) | 309-316 |
| Number of pages | 8 |
| Journal | Die Nahrung |
| Volume | 35 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1991 |
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ASJC Scopus subject areas
- Food Science
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Investigation of selected toxicological parameters of γ‐pentachlorocyclohexene (γ‐PCCH). / Mazzag, E.; Nagymajtényi, L.; Huszta, E.; Dési, I.; Macholz, R.
In: Die Nahrung, Vol. 35, No. 3, 1991, p. 309-316.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Investigation of selected toxicological parameters of γ‐pentachlorocyclohexene (γ‐PCCH)
AU - Mazzag, E.
AU - Nagymajtényi, L.
AU - Huszta, E.
AU - Dési, I.
AU - Macholz, R.
PY - 1991
Y1 - 1991
N2 - The toxic effects of the γ‐hexachlorocyclohexane metabolite γ‐pentachlorocyclohexene (γ‐PCCH) were studied by acute and subacute (6 weeks) experiments. The investigations included cerebral convulsibility with chemoshock (Tetrazolium), reactivity with hot plate method, the learning ability with learning tests, and peripheral nervous activity (EMG). Nociceptive reaction time was not influenced, the learning process (6 weeks) was inhibited by γ‐PCCH. The conduction velocity of the peripheral nerve was decreased. At the end of the 6th week liver enlargement was found.
AB - The toxic effects of the γ‐hexachlorocyclohexane metabolite γ‐pentachlorocyclohexene (γ‐PCCH) were studied by acute and subacute (6 weeks) experiments. The investigations included cerebral convulsibility with chemoshock (Tetrazolium), reactivity with hot plate method, the learning ability with learning tests, and peripheral nervous activity (EMG). Nociceptive reaction time was not influenced, the learning process (6 weeks) was inhibited by γ‐PCCH. The conduction velocity of the peripheral nerve was decreased. At the end of the 6th week liver enlargement was found.
UR - http://www.scopus.com/inward/record.url?scp=84984426566&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84984426566&partnerID=8YFLogxK
U2 - 10.1002/food.19910350310
DO - 10.1002/food.19910350310
M3 - Article
C2 - 1712426
AN - SCOPUS:84984426566
VL - 35
SP - 309
EP - 316
JO - Molecular Nutrition and Food Research
JF - Molecular Nutrition and Food Research
SN - 1613-4125
IS - 3
ER -