Investigation of selected toxicological parameters of γ‐pentachlorocyclohexene (γ‐PCCH)

E. Mazzag, L. Nagymajtényi, E. Huszta, I. Dési, R. Macholz

Research output: Contribution to journalArticle

Abstract

The toxic effects of the γ‐hexachlorocyclohexane metabolite γ‐pentachlorocyclohexene (γ‐PCCH) were studied by acute and subacute (6 weeks) experiments. The investigations included cerebral convulsibility with chemoshock (Tetrazolium), reactivity with hot plate method, the learning ability with learning tests, and peripheral nervous activity (EMG). Nociceptive reaction time was not influenced, the learning process (6 weeks) was inhibited by γ‐PCCH. The conduction velocity of the peripheral nerve was decreased. At the end of the 6th week liver enlargement was found.

Original languageEnglish
Pages (from-to)309-316
Number of pages8
JournalDie Nahrung
Volume35
Issue number3
DOIs
Publication statusPublished - 1991

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Toxicology
learning
Learning
Lindane
HCH (pesticide)
Aptitude
peripheral nerves
Poisons
tetrazolium
Peripheral Nerves
Reaction Time
metabolites
liver
Liver
pentachlorocyclohexene
testing
methodology

ASJC Scopus subject areas

  • Food Science

Cite this

Investigation of selected toxicological parameters of γ‐pentachlorocyclohexene (γ‐PCCH). / Mazzag, E.; Nagymajtényi, L.; Huszta, E.; Dési, I.; Macholz, R.

In: Die Nahrung, Vol. 35, No. 3, 1991, p. 309-316.

Research output: Contribution to journalArticle

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