Investigation of production routes for the 161Ho Auger-electron emitting radiolanthanide, a candidate for therapy

F. Tárkányi, F. Ditrói, A. Hermanne, S. Takács, A. V. Ignatyuk

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The radiolanthanide 161Ho (2.48 h) is a promising Auger-electron emitter for internal radiotherapy that can be produced with particle accelerators. The excitation functions of the natDy(p,xn) 161Ho and natDy(d,x)161Ho reactions were measured up to 40 and 50 MeV respectively by using the stacked foil activation method and γ-ray spectrometry. The experimental data were compared with results of the TALYS code available in the TENDL 2011 library [1]. The main parameters of different production routes are discussed.

Original languageEnglish
Pages (from-to)277-286
Number of pages10
JournalJournal of Radioanalytical and Nuclear Chemistry
Volume298
Issue number1
DOIs
Publication statusPublished - 2013

Fingerprint

Particle Accelerators
Radiotherapy
Metal foil
Spectrometry
Libraries
Particle accelerators
Spectrum Analysis
Chemical activation
Electrons
Therapeutics

Keywords

  • Ho
  • Ho
  • Medical radioisotopes
  • Proton and deuteron irradiation
  • Therapeutical isotopes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Spectroscopy
  • Public Health, Environmental and Occupational Health
  • Pollution
  • Health, Toxicology and Mutagenesis
  • Nuclear Energy and Engineering
  • Analytical Chemistry

Cite this

@article{9f2137fd52d5460da7827a0f9fa4bd41,
title = "Investigation of production routes for the 161Ho Auger-electron emitting radiolanthanide, a candidate for therapy",
abstract = "The radiolanthanide 161Ho (2.48 h) is a promising Auger-electron emitter for internal radiotherapy that can be produced with particle accelerators. The excitation functions of the natDy(p,xn) 161Ho and natDy(d,x)161Ho reactions were measured up to 40 and 50 MeV respectively by using the stacked foil activation method and γ-ray spectrometry. The experimental data were compared with results of the TALYS code available in the TENDL 2011 library [1]. The main parameters of different production routes are discussed.",
keywords = "Ho, Ho, Medical radioisotopes, Proton and deuteron irradiation, Therapeutical isotopes",
author = "F. T{\'a}rk{\'a}nyi and F. Ditr{\'o}i and A. Hermanne and S. Tak{\'a}cs and Ignatyuk, {A. V.}",
year = "2013",
doi = "10.1007/s10967-012-2403-9",
language = "English",
volume = "298",
pages = "277--286",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
issn = "0022-4081",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Investigation of production routes for the 161Ho Auger-electron emitting radiolanthanide, a candidate for therapy

AU - Tárkányi, F.

AU - Ditrói, F.

AU - Hermanne, A.

AU - Takács, S.

AU - Ignatyuk, A. V.

PY - 2013

Y1 - 2013

N2 - The radiolanthanide 161Ho (2.48 h) is a promising Auger-electron emitter for internal radiotherapy that can be produced with particle accelerators. The excitation functions of the natDy(p,xn) 161Ho and natDy(d,x)161Ho reactions were measured up to 40 and 50 MeV respectively by using the stacked foil activation method and γ-ray spectrometry. The experimental data were compared with results of the TALYS code available in the TENDL 2011 library [1]. The main parameters of different production routes are discussed.

AB - The radiolanthanide 161Ho (2.48 h) is a promising Auger-electron emitter for internal radiotherapy that can be produced with particle accelerators. The excitation functions of the natDy(p,xn) 161Ho and natDy(d,x)161Ho reactions were measured up to 40 and 50 MeV respectively by using the stacked foil activation method and γ-ray spectrometry. The experimental data were compared with results of the TALYS code available in the TENDL 2011 library [1]. The main parameters of different production routes are discussed.

KW - Ho

KW - Ho

KW - Medical radioisotopes

KW - Proton and deuteron irradiation

KW - Therapeutical isotopes

UR - http://www.scopus.com/inward/record.url?scp=84885179977&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885179977&partnerID=8YFLogxK

U2 - 10.1007/s10967-012-2403-9

DO - 10.1007/s10967-012-2403-9

M3 - Article

VL - 298

SP - 277

EP - 286

JO - Journal of Radioanalytical and Nuclear Chemistry

JF - Journal of Radioanalytical and Nuclear Chemistry

SN - 0022-4081

IS - 1

ER -