Echinops fajok poliszacharidjainak tanulmanyozasa gyogynoveny poliszacharidok I.

Translated title of the contribution: Investigation of polysaccharides of Echinops species. Medicinal plant polysaccharides I.

Zsolt Horváth, G. Gyémánt, Béla Dános, Pál Nánási

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Polysaccharides isolated from Echinops sphaerocephalus, Echinops ruthenicus, Echinops exaltatus, Echinops commutatus and Echinops orientalis (Asteraceae family) were investigated to study their qualitative and quantitative relations. The extracts of these studied plants have been used in traditional Chinese medicine as drugs with anti-inflammatory effect and anti-tumor promoting action in the osseous system [1]. We suppose that these biological effects are related to the polysaccharides especially to the acidic ones. The plant material was successively extracted with boiling water and six fractions were collected. The yield was 40-45%. The uronic acid content of these fractions, measured by the Bitter method, was relatively high 15-35% (Table I.). In case of Echinops sphaerocephalus different parts of the plant were investigated. The root and the stem are useful from a practical point of view because of the high uronic acid content. Some fractions, which seemed to be interesting on the basis of the measured uronic acid content, were dialyzed then concentrated, lyophilized and their uronic acid, protein and carbohydrate contents were determinated (Table III). The Echinops orientalis root fraction 6, was separated by ion-exchange chromatography. The monosaccharide composition of the neutral and the acidic fractions was measured by gas chromatography (Table IV).

Original languageHungarian
Pages (from-to)214-219
Number of pages6
JournalActa Pharmaceutica Hungarica
Volume68
Issue number4
Publication statusPublished - Jul 1998

Fingerprint

Uronic Acids
Medicinal Plants
Polysaccharides
Asteraceae
Monosaccharides
Chinese Traditional Medicine
Plant Extracts
Ion Exchange Chromatography
Gas Chromatography
Anti-Inflammatory Agents
Carbohydrates
Water
Pharmaceutical Preparations
Neoplasms
Proteins

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Echinops fajok poliszacharidjainak tanulmanyozasa gyogynoveny poliszacharidok I. / Horváth, Zsolt; Gyémánt, G.; Dános, Béla; Nánási, Pál.

In: Acta Pharmaceutica Hungarica, Vol. 68, No. 4, 07.1998, p. 214-219.

Research output: Contribution to journalArticle

Horváth, Zsolt ; Gyémánt, G. ; Dános, Béla ; Nánási, Pál. / Echinops fajok poliszacharidjainak tanulmanyozasa gyogynoveny poliszacharidok I. In: Acta Pharmaceutica Hungarica. 1998 ; Vol. 68, No. 4. pp. 214-219.
@article{575a00c4e7844064b0ae03a1e1dedb24,
title = "Echinops fajok poliszacharidjainak tanulmanyozasa gyogynoveny poliszacharidok I.",
abstract = "Polysaccharides isolated from Echinops sphaerocephalus, Echinops ruthenicus, Echinops exaltatus, Echinops commutatus and Echinops orientalis (Asteraceae family) were investigated to study their qualitative and quantitative relations. The extracts of these studied plants have been used in traditional Chinese medicine as drugs with anti-inflammatory effect and anti-tumor promoting action in the osseous system [1]. We suppose that these biological effects are related to the polysaccharides especially to the acidic ones. The plant material was successively extracted with boiling water and six fractions were collected. The yield was 40-45{\%}. The uronic acid content of these fractions, measured by the Bitter method, was relatively high 15-35{\%} (Table I.). In case of Echinops sphaerocephalus different parts of the plant were investigated. The root and the stem are useful from a practical point of view because of the high uronic acid content. Some fractions, which seemed to be interesting on the basis of the measured uronic acid content, were dialyzed then concentrated, lyophilized and their uronic acid, protein and carbohydrate contents were determinated (Table III). The Echinops orientalis root fraction 6, was separated by ion-exchange chromatography. The monosaccharide composition of the neutral and the acidic fractions was measured by gas chromatography (Table IV).",
author = "Zsolt Horv{\'a}th and G. Gy{\'e}m{\'a}nt and B{\'e}la D{\'a}nos and P{\'a}l N{\'a}n{\'a}si",
year = "1998",
month = "7",
language = "Hungarian",
volume = "68",
pages = "214--219",
journal = "Acta Pharmaceutica Hungarica",
issn = "0001-6659",
publisher = "Magyar Gyogyszereszeti Tarsasag",
number = "4",

}

TY - JOUR

T1 - Echinops fajok poliszacharidjainak tanulmanyozasa gyogynoveny poliszacharidok I.

AU - Horváth, Zsolt

AU - Gyémánt, G.

AU - Dános, Béla

AU - Nánási, Pál

PY - 1998/7

Y1 - 1998/7

N2 - Polysaccharides isolated from Echinops sphaerocephalus, Echinops ruthenicus, Echinops exaltatus, Echinops commutatus and Echinops orientalis (Asteraceae family) were investigated to study their qualitative and quantitative relations. The extracts of these studied plants have been used in traditional Chinese medicine as drugs with anti-inflammatory effect and anti-tumor promoting action in the osseous system [1]. We suppose that these biological effects are related to the polysaccharides especially to the acidic ones. The plant material was successively extracted with boiling water and six fractions were collected. The yield was 40-45%. The uronic acid content of these fractions, measured by the Bitter method, was relatively high 15-35% (Table I.). In case of Echinops sphaerocephalus different parts of the plant were investigated. The root and the stem are useful from a practical point of view because of the high uronic acid content. Some fractions, which seemed to be interesting on the basis of the measured uronic acid content, were dialyzed then concentrated, lyophilized and their uronic acid, protein and carbohydrate contents were determinated (Table III). The Echinops orientalis root fraction 6, was separated by ion-exchange chromatography. The monosaccharide composition of the neutral and the acidic fractions was measured by gas chromatography (Table IV).

AB - Polysaccharides isolated from Echinops sphaerocephalus, Echinops ruthenicus, Echinops exaltatus, Echinops commutatus and Echinops orientalis (Asteraceae family) were investigated to study their qualitative and quantitative relations. The extracts of these studied plants have been used in traditional Chinese medicine as drugs with anti-inflammatory effect and anti-tumor promoting action in the osseous system [1]. We suppose that these biological effects are related to the polysaccharides especially to the acidic ones. The plant material was successively extracted with boiling water and six fractions were collected. The yield was 40-45%. The uronic acid content of these fractions, measured by the Bitter method, was relatively high 15-35% (Table I.). In case of Echinops sphaerocephalus different parts of the plant were investigated. The root and the stem are useful from a practical point of view because of the high uronic acid content. Some fractions, which seemed to be interesting on the basis of the measured uronic acid content, were dialyzed then concentrated, lyophilized and their uronic acid, protein and carbohydrate contents were determinated (Table III). The Echinops orientalis root fraction 6, was separated by ion-exchange chromatography. The monosaccharide composition of the neutral and the acidic fractions was measured by gas chromatography (Table IV).

UR - http://www.scopus.com/inward/record.url?scp=0043284037&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0043284037&partnerID=8YFLogxK

M3 - Article

C2 - 9737021

AN - SCOPUS:0043284037

VL - 68

SP - 214

EP - 219

JO - Acta Pharmaceutica Hungarica

JF - Acta Pharmaceutica Hungarica

SN - 0001-6659

IS - 4

ER -