Investigation of Enantiomer Bonding on a Chiral Stationary Phase by FT-Raman Spectrometry

E. Horváth, L. Kocsis, R. L. Frost, B. Hren, L. P. Szabó

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The bonding of serine, phenylalanine, and mandelic acid enantiomers on an N-3,5-dinitrobenzoyl-L-leucine chiral stationary phase (on zeolite A support) has been investigated by FT-Raman spectrometry. It was found that retention is due to hydrogen bonds and π-stacking interactions between the stationary phase and the analyte. The involvement of the two different amide groups (as donor and/or acceptor) in the complexation reaction can be followed based on spectral data. A correlation was found between the ratio of the amide I and the ring stretching (1532 cm-1) bands and retention data.

Original languageEnglish
Pages (from-to)2766-2770
Number of pages5
JournalAnalytical Chemistry
Volume70
Issue number13
Publication statusPublished - Jul 1 1998

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Enantiomers
Amides
Spectrometry
Zeolites
Complexation
Phenylalanine
Leucine
Serine
Stretching
Hydrogen bonds
mandelic acid

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Horváth, E., Kocsis, L., Frost, R. L., Hren, B., & Szabó, L. P. (1998). Investigation of Enantiomer Bonding on a Chiral Stationary Phase by FT-Raman Spectrometry. Analytical Chemistry, 70(13), 2766-2770.

Investigation of Enantiomer Bonding on a Chiral Stationary Phase by FT-Raman Spectrometry. / Horváth, E.; Kocsis, L.; Frost, R. L.; Hren, B.; Szabó, L. P.

In: Analytical Chemistry, Vol. 70, No. 13, 01.07.1998, p. 2766-2770.

Research output: Contribution to journalArticle

Horváth, E, Kocsis, L, Frost, RL, Hren, B & Szabó, LP 1998, 'Investigation of Enantiomer Bonding on a Chiral Stationary Phase by FT-Raman Spectrometry', Analytical Chemistry, vol. 70, no. 13, pp. 2766-2770.
Horváth, E. ; Kocsis, L. ; Frost, R. L. ; Hren, B. ; Szabó, L. P. / Investigation of Enantiomer Bonding on a Chiral Stationary Phase by FT-Raman Spectrometry. In: Analytical Chemistry. 1998 ; Vol. 70, No. 13. pp. 2766-2770.
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