Investigation of antimicrobial, antioxidant, and xanthine oxidase-inhibitory activities of Phellinus (Agaricomycetes) mushroom species native to Central Europe

Bernadett Kovács, Zoltán Péter Zomborszki, Orsolya Orbán-Gyapai, Boglárka Csupor-Löffler, Erika Liktor-Busa, Andrea Lázár, Viktor Papp, Edit Urbán, J. Hohmann, Attila Ványolós

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Ten representative Central European phellinoid Hymenochaetaceae species (Phellinus sensu lato) were selected to examine their potential pharmacological activity. In this study 40 organic (n-hexane, chloroform, 50% methanol) and aqueous extracts with different polarities were analyzed for their antimicrobial, antioxidant, and xan­thine oxidase (XO)-inhibitory properties. Fomitiporia robusta, Fuscoporia torulosa, Phellopilus nigrolimitatus, and Porodaedalea chrysoloma showed moderate antibacterial activity; Bacillus subtilis ATCC 6633, methicillin-resistant Staphylococcus aureus ATCC 43300, and Moraxella catarrhalis ATCC 43617 were the strains most susceptible to the examined fungal species. The in vitro antioxidant and XO assays demonstrated that most of the selected species possess remarkable antioxidant and XO-inhibitory activities. The water extracts in general proved to be more active antioxidants than organic extracts. In the case of F. torulosa, Ph. nigrolimitatus, and P. chrysoloma, the results of DPPH tests correlate well with those obtained by oxygen radical absorbance capacity tests; these mushrooms pre­sented high antioxidant activities in both assays. Future studies involving phellinoid Hymenochaetaceae species are planned, which may furnish novel results in terms of the species’ pharmacological activity and the specific compounds responsible for the observed activity.

Original languageEnglish
Pages (from-to)387-394
Number of pages8
JournalInternational Journal of Medicinal Mushrooms
Volume19
Issue number5
DOIs
Publication statusPublished - Jan 1 2017

Fingerprint

Xanthine Oxidase
Agaricales
Antioxidants
Pharmacology
Moraxella (Branhamella) catarrhalis
Methicillin-Resistant Staphylococcus aureus
Chloroform
Bacillus subtilis
Methanol
Water

Keywords

  • Antimicrobial
  • Antioxidant
  • Medicinal mushrooms
  • Phellinus
  • Xanthine oxidase inhibitory activity

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Pharmacology
  • Drug Discovery

Cite this

Investigation of antimicrobial, antioxidant, and xanthine oxidase-inhibitory activities of Phellinus (Agaricomycetes) mushroom species native to Central Europe. / Kovács, Bernadett; Zomborszki, Zoltán Péter; Orbán-Gyapai, Orsolya; Csupor-Löffler, Boglárka; Liktor-Busa, Erika; Lázár, Andrea; Papp, Viktor; Urbán, Edit; Hohmann, J.; Ványolós, Attila.

In: International Journal of Medicinal Mushrooms, Vol. 19, No. 5, 01.01.2017, p. 387-394.

Research output: Contribution to journalArticle

Kovács, Bernadett ; Zomborszki, Zoltán Péter ; Orbán-Gyapai, Orsolya ; Csupor-Löffler, Boglárka ; Liktor-Busa, Erika ; Lázár, Andrea ; Papp, Viktor ; Urbán, Edit ; Hohmann, J. ; Ványolós, Attila. / Investigation of antimicrobial, antioxidant, and xanthine oxidase-inhibitory activities of Phellinus (Agaricomycetes) mushroom species native to Central Europe. In: International Journal of Medicinal Mushrooms. 2017 ; Vol. 19, No. 5. pp. 387-394.
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