Investigation of a series of neuroactive glycine dipeptide derivatives by fast‐atom bombardment and mass‐selected collision‐induced dissociation mass spectrometry

Maria Henczi, Donald F. Weaver, J. Borossay

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Glycylglycine (glygly) and 40 related acetamide derivatives were synthesized and investigated by fast‐atom bombardment mass spectrometry. The protonated molecules were mass selected and their collision‐induced dissociations were analyzed by tandem mass spectrometry. The data obtained allow a fragmentation pattern to be established for these glygly analogues and permit detailed structural information on the main fragment ions to be ascertained.

Original languageEnglish
Pages (from-to)134-138
Number of pages5
JournalRapid Communications in Mass Spectrometry
Volume8
Issue number1
DOIs
Publication statusPublished - 1994

Fingerprint

Dipeptides
Glycine
Mass spectrometry
Glycylglycine
Derivatives
Ions
Molecules
acetamide

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Organic Chemistry

Cite this

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abstract = "Glycylglycine (glygly) and 40 related acetamide derivatives were synthesized and investigated by fast‐atom bombardment mass spectrometry. The protonated molecules were mass selected and their collision‐induced dissociations were analyzed by tandem mass spectrometry. The data obtained allow a fragmentation pattern to be established for these glygly analogues and permit detailed structural information on the main fragment ions to be ascertained.",
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AU - Borossay, J.

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AB - Glycylglycine (glygly) and 40 related acetamide derivatives were synthesized and investigated by fast‐atom bombardment mass spectrometry. The protonated molecules were mass selected and their collision‐induced dissociations were analyzed by tandem mass spectrometry. The data obtained allow a fragmentation pattern to be established for these glygly analogues and permit detailed structural information on the main fragment ions to be ascertained.

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