Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity

I. Horváth, Ádám Németh, Zsófia Lenkey, Nicola Alessandri, Fabrizio Tufano, Pál Kis, Balázs Gaszner, Attila Cziráki

Research output: Contribution to journalArticle

215 Citations (Scopus)

Abstract

Background: The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements. Methods: Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph. Results: We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (r = 0.9, P <0.001; r = 0.94, P <0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (r = 0.95, P <0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the 'B' grading. The PWVao values measured invasively and by Arteriograph were 9.41 ± 1.8 m/s and 9.46 ± 1.8 m/s, respectively (mean ± SD); furthermore, the Pearsons correlation was 0.91 (P <0.001). The limits of agreement were 11.4% for aortic Aix and 1.59 m/s for PWVao. Conclusion: Aix, SBPao and PWVao, measured oscillometrically, showed strong correlation with the invasively obtained values. The observed limits of agreement are encouragingly low for accepting the method for clinical use. Our results suggest that the PWVao values, measured by Arteriograph, are close to the true aortic PWV, determined invasively.

Original languageEnglish
Pages (from-to)2068-2075
Number of pages8
JournalJournal of Hypertension
Volume28
Issue number10
DOIs
Publication statusPublished - Oct 2010

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Pulse Wave Analysis
Arterial Pressure
Blood Pressure
Equipment and Supplies
Cardiac Catheterization
Arm

Keywords

  • arterial stiffness
  • Arteriograph
  • augmentation index
  • invasive measurement
  • oscillometric method
  • pulse wave velocity
  • validation

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity. / Horváth, I.; Németh, Ádám; Lenkey, Zsófia; Alessandri, Nicola; Tufano, Fabrizio; Kis, Pál; Gaszner, Balázs; Cziráki, Attila.

In: Journal of Hypertension, Vol. 28, No. 10, 10.2010, p. 2068-2075.

Research output: Contribution to journalArticle

Horváth, I. ; Németh, Ádám ; Lenkey, Zsófia ; Alessandri, Nicola ; Tufano, Fabrizio ; Kis, Pál ; Gaszner, Balázs ; Cziráki, Attila. / Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity. In: Journal of Hypertension. 2010 ; Vol. 28, No. 10. pp. 2068-2075.
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abstract = "Background: The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements. Methods: Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph. Results: We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (r = 0.9, P <0.001; r = 0.94, P <0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (r = 0.95, P <0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the 'B' grading. The PWVao values measured invasively and by Arteriograph were 9.41 ± 1.8 m/s and 9.46 ± 1.8 m/s, respectively (mean ± SD); furthermore, the Pearsons correlation was 0.91 (P <0.001). The limits of agreement were 11.4{\%} for aortic Aix and 1.59 m/s for PWVao. Conclusion: Aix, SBPao and PWVao, measured oscillometrically, showed strong correlation with the invasively obtained values. The observed limits of agreement are encouragingly low for accepting the method for clinical use. Our results suggest that the PWVao values, measured by Arteriograph, are close to the true aortic PWV, determined invasively.",
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AU - Horváth, I.

AU - Németh, Ádám

AU - Lenkey, Zsófia

AU - Alessandri, Nicola

AU - Tufano, Fabrizio

AU - Kis, Pál

AU - Gaszner, Balázs

AU - Cziráki, Attila

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N2 - Background: The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements. Methods: Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph. Results: We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (r = 0.9, P <0.001; r = 0.94, P <0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (r = 0.95, P <0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the 'B' grading. The PWVao values measured invasively and by Arteriograph were 9.41 ± 1.8 m/s and 9.46 ± 1.8 m/s, respectively (mean ± SD); furthermore, the Pearsons correlation was 0.91 (P <0.001). The limits of agreement were 11.4% for aortic Aix and 1.59 m/s for PWVao. Conclusion: Aix, SBPao and PWVao, measured oscillometrically, showed strong correlation with the invasively obtained values. The observed limits of agreement are encouragingly low for accepting the method for clinical use. Our results suggest that the PWVao values, measured by Arteriograph, are close to the true aortic PWV, determined invasively.

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