Introduction of click chemistry to carotenoids

Magdolna Háda, Veronika Nagy, Anikó Takátsy, József Deli, Jan Hait, Attila Agócs

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We describe the synthesis of carotenoid derivatives via the azide-alkyne click reaction and optimize the conditions for these sensitive molecules. After finding the mildest conditions possible for the reaction we were able to use the click reaction for the synthesis of PEG-carotenoid conjugates starting from carotenoid pentynoates and PEG azides.

Original languageEnglish
Pages (from-to)2480-2482
Number of pages3
JournalTetrahedron Letters
Volume53
Issue number19
DOIs
Publication statusPublished - May 9 2012

Keywords

  • Azide-alkyne click reaction
  • Carotenoid
  • Ester
  • PEG conjugates

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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