Intravascular large B-cell lymphoma

Remission after rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy

Barbara Horváth, J. Demeter, Nóra Eros, Judit Hársing, Judit Csomor, A. Matolcsy, Gyula Bottlik, Gabriella Gyori, Márta Marschalkó, S. Kárpáti

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Intravascular lymphoma is an uncommon, very aggressive extranodal non-Hodgkin lymphoma that most frequently involves the skin and central nervous system. Most cases are of B-cell origin; T-cell phenotype is extremely rare. Malignant cells proliferate within the lumens of capillaries, arterioles, venules, and small arteries; vascular occlusion is responsible for the clinical signs and symptoms. The prognosis of this high-grade B-cell lymphoma has improved since the introduction of the anti-CD20 monoclonal antibody, rituximab. We describe a case of B-cell intravascular lymphoma successfully treated with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisolone.

Original languageEnglish
Pages (from-to)885-888
Number of pages4
JournalJournal of the American Academy of Dermatology
Volume61
Issue number5
DOIs
Publication statusPublished - Nov 2009

Fingerprint

Vincristine
B-Cell Lymphoma
Prednisolone
Non-Hodgkin's Lymphoma
Doxorubicin
Cyclophosphamide
Drug Therapy
Venules
Arterioles
Signs and Symptoms
Blood Vessels
Lymphoma
B-Lymphocytes
Central Nervous System
Arteries
Monoclonal Antibodies
T-Lymphocytes
Phenotype
Skin
Rituximab

Keywords

  • CHOP
  • intravascular large B-cell lymphoma
  • rituximab

ASJC Scopus subject areas

  • Dermatology

Cite this

Intravascular large B-cell lymphoma : Remission after rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy. / Horváth, Barbara; Demeter, J.; Eros, Nóra; Hársing, Judit; Csomor, Judit; Matolcsy, A.; Bottlik, Gyula; Gyori, Gabriella; Marschalkó, Márta; Kárpáti, S.

In: Journal of the American Academy of Dermatology, Vol. 61, No. 5, 11.2009, p. 885-888.

Research output: Contribution to journalArticle

Horváth, Barbara ; Demeter, J. ; Eros, Nóra ; Hársing, Judit ; Csomor, Judit ; Matolcsy, A. ; Bottlik, Gyula ; Gyori, Gabriella ; Marschalkó, Márta ; Kárpáti, S. / Intravascular large B-cell lymphoma : Remission after rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy. In: Journal of the American Academy of Dermatology. 2009 ; Vol. 61, No. 5. pp. 885-888.
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AU - Csomor, Judit

AU - Matolcsy, A.

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