Interacting biological and electronic neurons generate realistic oscillatory rhythms

A. Szűcs, Pablo Varona, Alexander R. Volkovskii, Henry D I Abarbanel, Mikhail I. Rabinovich, Allen I. Selverston

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Small assemblies of neurons such as central pattern generators (CPG) are known to express regular oscillatory firing patterns comprising bursts of action potentials. In contrast, individual CPG neurons isolated from the remainder of the network can generate irregular firing patterns. In our study of cooperative behavior in CPGs we developed an analog electronic neuron (EN) that reproduces firing patterns observed in lobster pyloric CPG neurons. Using a tuneable artificial synapse we connected the EN bidirectionally to neurons of this CPG. We found that the periodic bursting oscillation of this mixed assembly depends on the strength and sign of the electrical coupling. Working with identified, isolated pyloric CPG neurons whose network rhythms were impaired, the EN/biological network restored the characteristic CPG rhythm both when the EN oscillations are regular and when they are irregular. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish
Pages (from-to)563-569
Number of pages7
JournalNeuroReport
Volume11
Issue number3
Publication statusPublished - 2000

Fingerprint

Central Pattern Generators
Neurons
Synapses
Action Potentials
Cooperative Behavior

Keywords

  • Electronic neuron
  • Electronic synapse
  • Oscillatory rhythm
  • Pyloric neurons
  • Regularization
  • Synchronization

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Szűcs, A., Varona, P., Volkovskii, A. R., Abarbanel, H. D. I., Rabinovich, M. I., & Selverston, A. I. (2000). Interacting biological and electronic neurons generate realistic oscillatory rhythms. NeuroReport, 11(3), 563-569.

Interacting biological and electronic neurons generate realistic oscillatory rhythms. / Szűcs, A.; Varona, Pablo; Volkovskii, Alexander R.; Abarbanel, Henry D I; Rabinovich, Mikhail I.; Selverston, Allen I.

In: NeuroReport, Vol. 11, No. 3, 2000, p. 563-569.

Research output: Contribution to journalArticle

Szűcs, A, Varona, P, Volkovskii, AR, Abarbanel, HDI, Rabinovich, MI & Selverston, AI 2000, 'Interacting biological and electronic neurons generate realistic oscillatory rhythms', NeuroReport, vol. 11, no. 3, pp. 563-569.
Szűcs A, Varona P, Volkovskii AR, Abarbanel HDI, Rabinovich MI, Selverston AI. Interacting biological and electronic neurons generate realistic oscillatory rhythms. NeuroReport. 2000;11(3):563-569.
Szűcs, A. ; Varona, Pablo ; Volkovskii, Alexander R. ; Abarbanel, Henry D I ; Rabinovich, Mikhail I. ; Selverston, Allen I. / Interacting biological and electronic neurons generate realistic oscillatory rhythms. In: NeuroReport. 2000 ; Vol. 11, No. 3. pp. 563-569.
@article{a2e8bc43e7ee4496a85068f2455b5004,
title = "Interacting biological and electronic neurons generate realistic oscillatory rhythms",
abstract = "Small assemblies of neurons such as central pattern generators (CPG) are known to express regular oscillatory firing patterns comprising bursts of action potentials. In contrast, individual CPG neurons isolated from the remainder of the network can generate irregular firing patterns. In our study of cooperative behavior in CPGs we developed an analog electronic neuron (EN) that reproduces firing patterns observed in lobster pyloric CPG neurons. Using a tuneable artificial synapse we connected the EN bidirectionally to neurons of this CPG. We found that the periodic bursting oscillation of this mixed assembly depends on the strength and sign of the electrical coupling. Working with identified, isolated pyloric CPG neurons whose network rhythms were impaired, the EN/biological network restored the characteristic CPG rhythm both when the EN oscillations are regular and when they are irregular. (C) 2000 Lippincott Williams and Wilkins.",
keywords = "Electronic neuron, Electronic synapse, Oscillatory rhythm, Pyloric neurons, Regularization, Synchronization",
author = "A. Szűcs and Pablo Varona and Volkovskii, {Alexander R.} and Abarbanel, {Henry D I} and Rabinovich, {Mikhail I.} and Selverston, {Allen I.}",
year = "2000",
language = "English",
volume = "11",
pages = "563--569",
journal = "NeuroReport",
issn = "0959-4965",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Interacting biological and electronic neurons generate realistic oscillatory rhythms

AU - Szűcs, A.

AU - Varona, Pablo

AU - Volkovskii, Alexander R.

AU - Abarbanel, Henry D I

AU - Rabinovich, Mikhail I.

AU - Selverston, Allen I.

PY - 2000

Y1 - 2000

N2 - Small assemblies of neurons such as central pattern generators (CPG) are known to express regular oscillatory firing patterns comprising bursts of action potentials. In contrast, individual CPG neurons isolated from the remainder of the network can generate irregular firing patterns. In our study of cooperative behavior in CPGs we developed an analog electronic neuron (EN) that reproduces firing patterns observed in lobster pyloric CPG neurons. Using a tuneable artificial synapse we connected the EN bidirectionally to neurons of this CPG. We found that the periodic bursting oscillation of this mixed assembly depends on the strength and sign of the electrical coupling. Working with identified, isolated pyloric CPG neurons whose network rhythms were impaired, the EN/biological network restored the characteristic CPG rhythm both when the EN oscillations are regular and when they are irregular. (C) 2000 Lippincott Williams and Wilkins.

AB - Small assemblies of neurons such as central pattern generators (CPG) are known to express regular oscillatory firing patterns comprising bursts of action potentials. In contrast, individual CPG neurons isolated from the remainder of the network can generate irregular firing patterns. In our study of cooperative behavior in CPGs we developed an analog electronic neuron (EN) that reproduces firing patterns observed in lobster pyloric CPG neurons. Using a tuneable artificial synapse we connected the EN bidirectionally to neurons of this CPG. We found that the periodic bursting oscillation of this mixed assembly depends on the strength and sign of the electrical coupling. Working with identified, isolated pyloric CPG neurons whose network rhythms were impaired, the EN/biological network restored the characteristic CPG rhythm both when the EN oscillations are regular and when they are irregular. (C) 2000 Lippincott Williams and Wilkins.

KW - Electronic neuron

KW - Electronic synapse

KW - Oscillatory rhythm

KW - Pyloric neurons

KW - Regularization

KW - Synchronization

UR - http://www.scopus.com/inward/record.url?scp=0034000323&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034000323&partnerID=8YFLogxK

M3 - Article

C2 - 10718315

AN - SCOPUS:0034000323

VL - 11

SP - 563

EP - 569

JO - NeuroReport

JF - NeuroReport

SN - 0959-4965

IS - 3

ER -