Inter-strain comparison by pyrolysis mass spectrometry of Staphylococcus aureus isolates associated with nosocomial infection

P. R. Sisson, E. Nagy, Z. Kòczián, E. Veszelovsky, R. Freeman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Pyrolysis mass spectrometry was used to characterise Straphylococcus aureus isolates from an outbreak of postoperative wound infections on a mixed surgical ward. The PyMS results were compared with those of phage typing. Both suggested a single strain of S. aureus, of phage type 3C,55,71, was responsible for six of the 13 wound infections. PyMS differentiated an isolate from a member of staff of similar phage type to the epidemic strain, which had previously been considered to be the point source for the outbreak. PyMS is a rapid and inexpensive technique for investigating nosocomial outbreaks, including those caused by S. aureus and, in this instance, was more discriminatory than phage typing.

Original languageEnglish
Pages (from-to)327-330
Number of pages4
JournalAntonie van Leeuwenhoek, International Journal of General and Molecular Microbiology
Volume73
Issue number4
DOIs
Publication statusPublished - Dec 2 1998

Keywords

  • Nosocomial infection
  • Pyrolysis mass spectrometry
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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