Intensity dependence of auditory evoked potentials in behaving cats

Georg Juckel, V. Csépe, M. Molnár, Ulrich Hegerl, G. Karmos

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The intensity dependence of auditory evoked potentials (AEPs) recorded epidurally over the primary (AI) and secondary (AII) areas of the auditory cortex was studied in behaving cats during wakefulness, sleep and anesthesia. Four kHz tones of 50, 60, 70, and 80 dB SPL, presented in random order every 2 ± 0.2 s by a bone conductor, elicited clear changes of the AEP amplitudes with increasing stimulus intensity, but individual components displayed different response curves. AEP components from the AI region showed saturation of their amplitude with stimulus intensity (P13, P34) or no amplitude increase (N19), while amplitude and intensity were linearly related in the AII area. The intensity dependence of the first positive component (P12/P13) was consistently stronger for the AEP recorded from the AI than from the AII area, while later components exhibited no difference between AI and AII. During slow wave sleep, the intensity dependence of this first positive component increased in the two areas, while that of later components decreased. Pentobarbital anesthesia abolished almost all later components and depressed the intensity dependence of the first positive component both in the AI and AII area. These results indicate that (1) clear intensity dependence of AEP exists in the cat auditory cortex and (2) this intensity dependence, especially that of the first positive AEP component, shares functional similarities to the human augmenting/reducing phenomenon in the auditory modality concerning regional differences and sleep-waking cycle.

Original languageEnglish
Pages (from-to)527-537
Number of pages11
JournalElectroencephalography and Clinical Neurophysiology - Evoked Potentials
Volume100
Issue number6
DOIs
Publication statusPublished - Nov 1996

Fingerprint

Auditory Evoked Potentials
Cats
Sleep
Auditory Cortex
Anesthesia
Wakefulness
Pentobarbital
Bone and Bones

Keywords

  • auditory cortex
  • auditory evoked potentials
  • augmenting/reducing
  • cat
  • tone intensity

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Intensity dependence of auditory evoked potentials in behaving cats. / Juckel, Georg; Csépe, V.; Molnár, M.; Hegerl, Ulrich; Karmos, G.

In: Electroencephalography and Clinical Neurophysiology - Evoked Potentials, Vol. 100, No. 6, 11.1996, p. 527-537.

Research output: Contribution to journalArticle

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