Insulin treatment (hormonal imprinting) increases the insulin production of the unicellular Tetrahymena long term. Is there a simultaneous formation of hormone receptor and hormone?

G. Csaba, P. Kovács

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Insulin treatment of Tetrahymena pyriformis resulted in a long-lasting increase in the insulin content of the cells. After about 200 generations, insulin levels significantly higher than in the control were demonstrated by using a quantitative immunocytochemical method. Although the insulin content fluctuated from day to day, it was always higher in the insulin pre-treated (imprinted) cells than in the controls. The results emphasise the simultaneous stimulation of hormone and receptor formation by hormonal imprinting.

Original languageEnglish
Pages (from-to)1011-1014
Number of pages4
JournalCell biology international
Issue number12
Publication statusPublished - Dec 1 1995


ASJC Scopus subject areas

  • Cell Biology

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