Insulin secretion and carbohydrate tolerance in childhood obesity

Research output: Contribution to journalReview article

6 Citations (Scopus)


The inability to clear glucose adequately from the blood is a common feature of obesity. The frequency of impaired glucose tolerance has been reported to vary from 11.5% to 74% on obese children: the causes of this discrepancy in the literature are discussed. Carbohydrate intolerance occurs in obesity in spite of the basal and reactive hyperinsulinaemia. This condition is termed insulin resistance, which can develop in several ways. The different theories concerning the primary cause or causes of insulin resistance in obesity are reviewed.

Original languageEnglish
Pages (from-to)131-135
Number of pages5
JournalKlinische Padiatrie
Issue number3
Publication statusPublished - Jan 1 1990


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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