Az inzulinszerü növekedési faktorokat kötö fehérjék.

Translated title of the contribution: Insulin-like growth factor proteins

Research output: Contribution to journalArticle

Abstract

The insulin-like growth factors circulate in plasma complex with a family of binding proteins that extend the serum half-life of the IGF peptides, transport the insulin-like growth factors to target cells, and modulate the interaction of the insulin-like growth factors with surface membrane receptors. The binding proteins have insulin-like growth factor-independent actions too, possibly by interacting with their own receptors on the cell membrane. The insulin-like growth factor binding protein superfamily consists of six classical binding proteins (-1, -2, -3, -4, -5, -6), and insulin-like growth factor binding protein-related proteins (-1, -2, -3, -4). Specific radioimmunoassays have been developed for the six classical binding proteins, the measurement of insulin-like growth factor binding protein-3 appears to have the greatest clinical value because it is growth hormone dependent.

Original languageHungarian
Pages (from-to)2349-2351
Number of pages3
JournalOrvosi Hetilap
Volume140
Issue number42
Publication statusPublished - Oct 17 1999

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Somatomedins
Insulin-Like Growth Factor Binding Proteins
Carrier Proteins
Insulin-Like Growth Factor Binding Protein 3
Proteins
Cell Communication
Growth Hormone
Radioimmunoassay
Half-Life
Cell Membrane
Peptides
Membranes
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Az inzulinszerü növekedési faktorokat kötö fehérjék. / Góth, M.

In: Orvosi Hetilap, Vol. 140, No. 42, 17.10.1999, p. 2349-2351.

Research output: Contribution to journalArticle

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