Insulin Binding Sites Induced in the Tetrahymena by Rat Liver Receptor Antibody

G. Csaba, P. Kovács, Ágnes Inczefi-Gonda

Research output: Contribution to journalArticle

10 Citations (Scopus)


Tetrahvmena cells treated with purified rabbit antibodies to rat hepatocellular membrane exhibited a considerable increase in binding capacity on reexposure to the antibody 24h later. Insulin binding was similarly enhanced by preexposure to the antibody, and vice versa, preexposure to insulin enhanced the later binding of rat liver receptor antibodies. This suggests that (1) the Tetrahymena and the rat possess similar insulin receptors, and (2) the receptor antibody is also able to induce imprinting for itself as well as for insulin. Concanavalin-A, noted for binding overlap with insulin, failed to induce imprinting either for insulin or for antibodies to receptors, whereas the latter did induce imprinting for Concanavalin-A.

Original languageEnglish
Pages (from-to)183-185
Number of pages3
JournalZeitschrift fur naturforschung - section c journal of biosciences
Issue number1-2
Publication statusPublished - Feb 1 1984


  • Binding Sites
  • Insulin
  • Receptor-antibody
  • Tetrahymena

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Insulin Binding Sites Induced in the Tetrahymena by Rat Liver Receptor Antibody'. Together they form a unique fingerprint.

  • Cite this