Institutional report - Thoracic general: Lung cancer as a second primary malignant tumor: Prognostic values after surgical resection

József Furák, Imre Troján, Tamás Szöke, A. Wolfárd, Ernest Nagy, István Németh, L. Tiszlavicz, G. Lazar

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Prognostic values of lung cancers as second primary malignant tumors (LC-as-SPTs) developed after a different type of first primary malignant tumor were analyzed. Forty-three patients underwent surgery for first primary malignant tumors and later for LC-as-SPTs. The most frequent first primary tumors were: 14 laryngo-pharyngeals; 7 lungs; and 5 colons. Only metachronous cases were included in our study, and the disease-free intervals (DFI) between the first and second primary tumors were divided into two groups: shorter than 36 months (DFI36). The survival was calculated from the time of surgery for LC-as-SPT. The 5-year overall survival rate was 38%. By univariate analysis, the 5-year survival was significantly lower in cases with DFI36 months (43%) (P=0.045), and in male (27%) than in female (62%) (P=0.032), and in N1 (31%) and N2 (0%) cases than in N0 (49%) cases (P=0.001). Using multivariate analysis with the previous factors, only the lymph node metastasis (P=0.001) had a significant impact on survival. The survival after LC-as-SPTs was shorter than after first primary lung cancer cases, and lymph node involvement had a significant impact on the postoperative survival based on uni- and multivariate analysis.

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalInteractive Cardiovascular and Thoracic Surgery
Volume7
Issue number1
DOIs
Publication statusPublished - Feb 2008

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Lung Neoplasms
Thorax
Neoplasms
Survival
Multivariate Analysis
Lymph Nodes
Colon
Survival Rate
Neoplasm Metastasis
Lung

Keywords

  • Disease-free interval
  • Lung cancer
  • Second primary malignant tumor

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Institutional report - Thoracic general : Lung cancer as a second primary malignant tumor: Prognostic values after surgical resection. / Furák, József; Troján, Imre; Szöke, Tamás; Wolfárd, A.; Nagy, Ernest; Németh, István; Tiszlavicz, L.; Lazar, G.

In: Interactive Cardiovascular and Thoracic Surgery, Vol. 7, No. 1, 02.2008, p. 50-53.

Research output: Contribution to journalArticle

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