Purified adenosine diphosphoribose transferase protein binds to RNA-DNA hybrid templates of reverse transcriptase at the DNA primer site and inhibits RT activity of HIV and MMu RTs. This action is prevented by auto-poly-ADP-ribosylation of the transferase but is reinduced by inhibitory ligands of the enzyme.
|Number of pages||8|
|Journal||Biochemical and biophysical research communications|
|Publication status||Published - Oct 31 1991|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology