The adhesion and multiplication of E.coli strain K12 with a derepressed synthesis of sex pili and of a nephropathogenic E.coli strain isolated from the urine of a patient with pyelonephritis, were demonstrated on the surface of cultured HEp-2 cells. The adhesion of the two E.coli strains was inhibited in the presence of 0.5-5.0 μg/ml promethazine or imipramine, but the multiplication of the bacteria on the monolayers was not decreased significantly in the presence of the two drugs. A scanning electromicroscopic technique was developed to study bacterial adhesion and colony formation on epithelial cells.
|Number of pages||9|
|Journal||Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A|
|Publication status||Published - Dec 1 1983|
ASJC Scopus subject areas