Inheritance of susceptibility and resistance to Rauscher leukaemia virus

F. D. Toth, L. Vaczi, M. Balogh

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Abstract

Susceptibility to Rauscher leukemia virus is determined by the 2 genes Rv 1 and Rv 2. Loci Rv 1 and Rv 2 determine the susceptibility to LLV and SFFV, respectively. On locus Rv 1 resistance and on locus Rv 2 susceptibility is dominant. The 2 genes segregate independently of each other. In Rv 2(S/S) and Rv 2(S/r) mice the degree of tumor specific antibody production is determined by the Rv 1 locus. In the case of genotype Rv 1(R/R) Rv 2(S/r), interferon production may be a factor determining resistance.

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalActa microbiologica Academiae Scientiarum Hungaricae
Volume20
Issue number3
Publication statusPublished - Dec 1 1973

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ASJC Scopus subject areas

  • Medicine(all)

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