Inheritance of susceptibility and resistance to Rauscher leukaemia virus

F. Tóth, L. Vaczi, M. Balogh

Research output: Contribution to journalArticle

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Abstract

Susceptibility to Rauscher leukemia virus is determined by the 2 genes Rv 1 and Rv 2. Loci Rv 1 and Rv 2 determine the susceptibility to LLV and SFFV, respectively. On locus Rv 1 resistance and on locus Rv 2 susceptibility is dominant. The 2 genes segregate independently of each other. In Rv 2(S/S) and Rv 2(S/r) mice the degree of tumor specific antibody production is determined by the Rv 1 locus. In the case of genotype Rv 1(R/R) Rv 2(S/r), interferon production may be a factor determining resistance.

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume20
Issue number3
Publication statusPublished - 1973

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Rauscher Virus
Spleen Focus-Forming Viruses
Neoplasm Antibodies
R Factors
Interferons
Genes
Antibody Formation
Genotype

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Inheritance of susceptibility and resistance to Rauscher leukaemia virus. / Tóth, F.; Vaczi, L.; Balogh, M.

In: Acta Microbiologica Academiae Scientiarum Hungaricae, Vol. 20, No. 3, 1973, p. 183-189.

Research output: Contribution to journalArticle

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