Infradiaphragmatic Hodgkin's disease

Árpád Illés, Györgyi Vadász, Anikó Bányai, Gyula Szegedi

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3 Citations (Scopus)

Abstract

Between 1968 and 1994, 133 patients with stages I and II supradiaphragmatic Hodgkin's disease were evaluated at our institution. During the same period we treated only 11 patients with stages I and 11 infradiaphragmatic Hodgkin's disease. When compared to patients with disease above the diaphragm, patients with Hodgkin's disease below the diaphragm were more frequently male (p < 0.05), were generally older (46.3 vs 40.1 years, but the difference was not significant), had a higher incidence of systemic symptoms (p < 0.05), and had predominantly histologic subtypes with mixed cellularity and lymphocyte predominance. Primary treatment included inverted Y radiotherapy in 3 patients, polychemotherapy in 6, and combined treatment in 2. Ten patients achieved complete response. Five- and ten-year survival rates were 90% and 67.5%, respectively. There was no difference in survival rate between patients with infradiaphragmatic and supradiaphragmatic Hodgkin's disease receiving similar treatment.

Original languageEnglish
Pages (from-to)117-122
Number of pages6
JournalHaematologia
Volume28
Issue number3
Publication statusPublished - Aug 25 1997

Keywords

  • Hodgkin's disease
  • Infradiaphragmatic
  • Survival

ASJC Scopus subject areas

  • Hematology

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  • Cite this

    Illés, Á., Vadász, G., Bányai, A., & Szegedi, G. (1997). Infradiaphragmatic Hodgkin's disease. Haematologia, 28(3), 117-122.