Objectives: The authors observed the prevalence of informative morphogenetic variants among schizophrenic, bipolar affective patients and normal controls. The data could enrich knowledge on the neurodevelopmental model of psychoses. Methods: The authors examined 56 informative morphogenetic variants in the case of 30 schizophrenic, 30 bipolar affective and 30 control persons. Results: The cumulative informative morphogenetic variant prevalence was significantly higher among schizophrenic patients than among bipolar affective patients (p<0.001) and control persons (p<0.001). Patients who suffered from schizophrenia had significantly higher rates of two minor malformations compared to bipolar patients, while schizophrenic patients had significantly higher rates of four minor malformations compared to control persons. Conclusion: The data support the neurodevelopmental model of schizophrenia and bipolar affectice disorder, but the findings suggest the need for further research in this field.
|Number of pages||7|
|Publication status||Published - Jan 1 2000|
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