Influence of treatment with prostaglandin synthesis inhibitor or progesterone on cytotoxic activity and progesterone binding capacity of lymphocytes during pregnancy

J. Szekeres-Barthó, V. Csernus, J. Hadnagy, A. S. Pacsa

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8 Citations (Scopus)

Abstract

Cytotoxic activity and progesterone binding capacity of lymphocytes obtained from women with threatened preterm labour were tested before and during treatment with acetylsalicylic acid or 17-hydroxyprogesterone caproate. Cytotoxic activity of the lymphocytes significantly decreased (p <0.001), while progesterone binding capacity significantly increased (p <0.001) following the introduction of the treatments. No changes in these parameters were observed on lymphocytes of untreated women. Preterm delivery occurred more frequently among untreated women than among women treated with acetylsalicylic acid (p <0.01) or those treated with 17-hydroxyprogesterone caproate (p <0.05).

Original languageEnglish
Pages (from-to)187-195
Number of pages9
JournalProstaglandins
Volume26
Issue number2
DOIs
Publication statusPublished - 1983

Fingerprint

Prostaglandin Antagonists
Lymphocytes
Prostaglandins
17-alpha-Hydroxyprogesterone
Progesterone
Pregnancy
Aspirin
Premature Obstetric Labor
Therapeutics
Personnel
17-alpha-hydroxy-progesterone caproate

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

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abstract = "Cytotoxic activity and progesterone binding capacity of lymphocytes obtained from women with threatened preterm labour were tested before and during treatment with acetylsalicylic acid or 17-hydroxyprogesterone caproate. Cytotoxic activity of the lymphocytes significantly decreased (p <0.001), while progesterone binding capacity significantly increased (p <0.001) following the introduction of the treatments. No changes in these parameters were observed on lymphocytes of untreated women. Preterm delivery occurred more frequently among untreated women than among women treated with acetylsalicylic acid (p <0.01) or those treated with 17-hydroxyprogesterone caproate (p <0.05).",
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T1 - Influence of treatment with prostaglandin synthesis inhibitor or progesterone on cytotoxic activity and progesterone binding capacity of lymphocytes during pregnancy

AU - Szekeres-Barthó, J.

AU - Csernus, V.

AU - Hadnagy, J.

AU - Pacsa, A. S.

PY - 1983

Y1 - 1983

N2 - Cytotoxic activity and progesterone binding capacity of lymphocytes obtained from women with threatened preterm labour were tested before and during treatment with acetylsalicylic acid or 17-hydroxyprogesterone caproate. Cytotoxic activity of the lymphocytes significantly decreased (p <0.001), while progesterone binding capacity significantly increased (p <0.001) following the introduction of the treatments. No changes in these parameters were observed on lymphocytes of untreated women. Preterm delivery occurred more frequently among untreated women than among women treated with acetylsalicylic acid (p <0.01) or those treated with 17-hydroxyprogesterone caproate (p <0.05).

AB - Cytotoxic activity and progesterone binding capacity of lymphocytes obtained from women with threatened preterm labour were tested before and during treatment with acetylsalicylic acid or 17-hydroxyprogesterone caproate. Cytotoxic activity of the lymphocytes significantly decreased (p <0.001), while progesterone binding capacity significantly increased (p <0.001) following the introduction of the treatments. No changes in these parameters were observed on lymphocytes of untreated women. Preterm delivery occurred more frequently among untreated women than among women treated with acetylsalicylic acid (p <0.01) or those treated with 17-hydroxyprogesterone caproate (p <0.05).

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