Segedanyagok hatasa szuszpenzios inhlacios aeroszolok hatekony szemcsemeret-tartomanyanak dozisonkenti mennyisegere

Translated title of the contribution: Influence of the auxiliary materials on the proportion of the effective particle size of metered-dose suspension-type aerosols

Lídia Fedina, Romána Zelkó, Laura Fedina, Zsuzsa Szabados, Márta Szántó, Gabriella Vakulya

Research output: Contribution to journalArticle

Abstract

The aim of the present study was to formulate suspension type inhalation aerosols by various types of auxiliary materials, and to select the formulation with the highest proportion of the effective particle size. The examined suspension type aerosol contained sodium cromoglycate as an active compound. For the stabilization of the suspension, the applied surface active ingredients were oleic acid and oleyl oleate, and dimethyl siloxane polymer was selected as hydrophobizing agent. Factorial design was used for the optimization of the experimental results. On the basis of our results, the correct types and amounts of auxiliary materials can be selected to obtain the therapeutically effective formulation.

Original languageHungarian
Pages (from-to)220-223
Number of pages4
JournalActa Pharmaceutica Hungarica
Volume68
Issue number4
Publication statusPublished - Jul 1998

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Aerosols
Particle Size
Suspensions
Siloxanes
Cromolyn Sodium
Oleic Acid
Inhalation
Polymers

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Segedanyagok hatasa szuszpenzios inhlacios aeroszolok hatekony szemcsemeret-tartomanyanak dozisonkenti mennyisegere. / Fedina, Lídia; Zelkó, Romána; Fedina, Laura; Szabados, Zsuzsa; Szántó, Márta; Vakulya, Gabriella.

In: Acta Pharmaceutica Hungarica, Vol. 68, No. 4, 07.1998, p. 220-223.

Research output: Contribution to journalArticle

Fedina, Lídia ; Zelkó, Romána ; Fedina, Laura ; Szabados, Zsuzsa ; Szántó, Márta ; Vakulya, Gabriella. / Segedanyagok hatasa szuszpenzios inhlacios aeroszolok hatekony szemcsemeret-tartomanyanak dozisonkenti mennyisegere. In: Acta Pharmaceutica Hungarica. 1998 ; Vol. 68, No. 4. pp. 220-223.
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