Influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood

G. Csaba, Sz Szeberenyi, O. Dobozy

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5 Citations (Scopus)

Abstract

A single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome P-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. This suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalMedical Biology
Volume64
Issue number4
Publication statusPublished - 1986

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Allylestrenol
Diethylstilbestrol
Steroids
Liver
Enzymes
Cytochrome P-450 Enzyme System
Testosterone

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood. / Csaba, G.; Szeberenyi, Sz; Dobozy, O.

In: Medical Biology, Vol. 64, No. 4, 1986, p. 197-200.

Research output: Contribution to journalArticle

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