Influence of physical activity on vertebral deformity in men and women: Results from the European Vertebral Osteoporosis Study

Alan J. Silman, T. W. O'Neill, C. Cooper, J. Kanis, D. Felsenberg, K. Abendroth, D. Agnusdei, A. Antoniou, A. Aroso, D. Banzer, L. I. Benevolenskaya, K. Bergmann, A. K. Bhalla, J. B Cannata Andia, S. Czekalski, P. D. Delmas, J. Dequeker, M. Diaz Curiel, J. B. Diaz Lopez, G. DilsenR. Eastell, J. A. Falch, B. Felsch, J. Franke, C. Gennari, P. Geusens, S. Havelka, A. Hofman, K. Hoszowski, I. Jajic, J. Janott, O. Johnell, L. Kalidis, S. Kirschner, C. Kiss, G. Krusekemper, T. Lauermann, A. Letkovska, A. Lopez Vaz, R. S. Lorenc, G. Lyritis, F. Marchand, D. Marsden, P. Masaryk, C. Matthis, J. Mews, H. E. Meyer, T. Miazgowski, E. E. Mikhailov, M. Naves Diaz, B. Nilsson, S. Ortoloni, G. Petta, H. A P Pols, G. Poór, A. Rapado, P. Raptou, H. Raspe, J. Reeve, D. M. Reid, W. Reisinger, F. Ring, D. Roig Escofet, M. Ruiz Martin, H. Schatz, C. Sheidt-Nave, M. Sosa, C. Todd, P. Vavrincova, J. Varlow, K. Weber, A. D. Woolf, E. Wieland, R. Williams, A. D. Woolf, R. Ziegler

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

Physical activity is associated with an increased bone mass and a reduced risk of hip fracture. There are, however, no data from population samples of men and women concerning the effect of regular levels of physical activity on the risk of vertebral deformity. The aim of this study was to determine the relationship between regular physical activity and vertebral deformity in European men and women. A population survey method was used. Thirty-six centers from 19 European countries participated. Each center recruited a population sample of men and women aged 50 years and over. Those who took part received an interviewer-administered questionnaire and lateral thoracolumbar radiographs. Subjects were asked about two dimensions of physical activity: (1) the level of physical activity undertaken either at work or at home on a daily basis at three different age periods: 15-25 years, 25-50 years, and 50+ years; and (2) the amount of time spent walking or cycling out of doors each day. Spinal radiographs were evaluated morphometrically and the presence of vertebral deformity was defined according to the McCloskey method. In total, 14,261 subjects, aged 50-79 years, from 30 centers were studied, of whom 809 (12.0%) men and 884 (11.7%) women had one or more deformities. After adjusting for age, center, smoking, and body mass index, very heavy levels of activity in all three age groups were associated with an increased risk of vertebral deformity in men (odds ratios, age adjusted [OR], 1.5-1.7; with all 95% confidence intervals [CI] excluding unity). No increased risk was observed in women. Current walking or cycling more than 1/4 h/day was associated with a reduced risk of vertebral deformity in women (OR 0.8; 95% CI 0.7-1.0). We conclude that regular walking in middle-aged and elderly women is associated with a reduced risk of vertebral deformity. By contrast, heavy levels of physical activity in early and middle adult life are associated with an increased risk in men. These differences are of relevance in understanding the epidemiology of vertebral deformity and planning programs of prevention.

Original languageEnglish
Pages (from-to)813-819
Number of pages7
JournalJournal of Bone and Mineral Research
Volume12
Issue number5
Publication statusPublished - 1997

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Osteoporosis
Exercise
Walking
Confidence Intervals
Population
Hip Fractures
Epidemiology
Body Mass Index
Age Groups
Smoking
Odds Ratio
Interviews
Bone and Bones

ASJC Scopus subject areas

  • Surgery

Cite this

Silman, A. J., O'Neill, T. W., Cooper, C., Kanis, J., Felsenberg, D., Abendroth, K., ... Ziegler, R. (1997). Influence of physical activity on vertebral deformity in men and women: Results from the European Vertebral Osteoporosis Study. Journal of Bone and Mineral Research, 12(5), 813-819.

Influence of physical activity on vertebral deformity in men and women : Results from the European Vertebral Osteoporosis Study. / Silman, Alan J.; O'Neill, T. W.; Cooper, C.; Kanis, J.; Felsenberg, D.; Abendroth, K.; Agnusdei, D.; Antoniou, A.; Aroso, A.; Banzer, D.; Benevolenskaya, L. I.; Bergmann, K.; Bhalla, A. K.; Andia, J. B Cannata; Czekalski, S.; Delmas, P. D.; Dequeker, J.; Diaz Curiel, M.; Diaz Lopez, J. B.; Dilsen, G.; Eastell, R.; Falch, J. A.; Felsch, B.; Franke, J.; Gennari, C.; Geusens, P.; Havelka, S.; Hofman, A.; Hoszowski, K.; Jajic, I.; Janott, J.; Johnell, O.; Kalidis, L.; Kirschner, S.; Kiss, C.; Krusekemper, G.; Lauermann, T.; Letkovska, A.; Vaz, A. Lopez; Lorenc, R. S.; Lyritis, G.; Marchand, F.; Marsden, D.; Masaryk, P.; Matthis, C.; Mews, J.; Meyer, H. E.; Miazgowski, T.; Mikhailov, E. E.; Diaz, M. Naves; Nilsson, B.; Ortoloni, S.; Petta, G.; Pols, H. A P; Poór, G.; Rapado, A.; Raptou, P.; Raspe, H.; Reeve, J.; Reid, D. M.; Reisinger, W.; Ring, F.; Escofet, D. Roig; Martin, M. Ruiz; Schatz, H.; Sheidt-Nave, C.; Sosa, M.; Todd, C.; Vavrincova, P.; Varlow, J.; Weber, K.; Woolf, A. D.; Wieland, E.; Williams, R.; Woolf, A. D.; Ziegler, R.

In: Journal of Bone and Mineral Research, Vol. 12, No. 5, 1997, p. 813-819.

Research output: Contribution to journalArticle

Silman, AJ, O'Neill, TW, Cooper, C, Kanis, J, Felsenberg, D, Abendroth, K, Agnusdei, D, Antoniou, A, Aroso, A, Banzer, D, Benevolenskaya, LI, Bergmann, K, Bhalla, AK, Andia, JBC, Czekalski, S, Delmas, PD, Dequeker, J, Diaz Curiel, M, Diaz Lopez, JB, Dilsen, G, Eastell, R, Falch, JA, Felsch, B, Franke, J, Gennari, C, Geusens, P, Havelka, S, Hofman, A, Hoszowski, K, Jajic, I, Janott, J, Johnell, O, Kalidis, L, Kirschner, S, Kiss, C, Krusekemper, G, Lauermann, T, Letkovska, A, Vaz, AL, Lorenc, RS, Lyritis, G, Marchand, F, Marsden, D, Masaryk, P, Matthis, C, Mews, J, Meyer, HE, Miazgowski, T, Mikhailov, EE, Diaz, MN, Nilsson, B, Ortoloni, S, Petta, G, Pols, HAP, Poór, G, Rapado, A, Raptou, P, Raspe, H, Reeve, J, Reid, DM, Reisinger, W, Ring, F, Escofet, DR, Martin, MR, Schatz, H, Sheidt-Nave, C, Sosa, M, Todd, C, Vavrincova, P, Varlow, J, Weber, K, Woolf, AD, Wieland, E, Williams, R, Woolf, AD & Ziegler, R 1997, 'Influence of physical activity on vertebral deformity in men and women: Results from the European Vertebral Osteoporosis Study', Journal of Bone and Mineral Research, vol. 12, no. 5, pp. 813-819.
Silman, Alan J. ; O'Neill, T. W. ; Cooper, C. ; Kanis, J. ; Felsenberg, D. ; Abendroth, K. ; Agnusdei, D. ; Antoniou, A. ; Aroso, A. ; Banzer, D. ; Benevolenskaya, L. I. ; Bergmann, K. ; Bhalla, A. K. ; Andia, J. B Cannata ; Czekalski, S. ; Delmas, P. D. ; Dequeker, J. ; Diaz Curiel, M. ; Diaz Lopez, J. B. ; Dilsen, G. ; Eastell, R. ; Falch, J. A. ; Felsch, B. ; Franke, J. ; Gennari, C. ; Geusens, P. ; Havelka, S. ; Hofman, A. ; Hoszowski, K. ; Jajic, I. ; Janott, J. ; Johnell, O. ; Kalidis, L. ; Kirschner, S. ; Kiss, C. ; Krusekemper, G. ; Lauermann, T. ; Letkovska, A. ; Vaz, A. Lopez ; Lorenc, R. S. ; Lyritis, G. ; Marchand, F. ; Marsden, D. ; Masaryk, P. ; Matthis, C. ; Mews, J. ; Meyer, H. E. ; Miazgowski, T. ; Mikhailov, E. E. ; Diaz, M. Naves ; Nilsson, B. ; Ortoloni, S. ; Petta, G. ; Pols, H. A P ; Poór, G. ; Rapado, A. ; Raptou, P. ; Raspe, H. ; Reeve, J. ; Reid, D. M. ; Reisinger, W. ; Ring, F. ; Escofet, D. Roig ; Martin, M. Ruiz ; Schatz, H. ; Sheidt-Nave, C. ; Sosa, M. ; Todd, C. ; Vavrincova, P. ; Varlow, J. ; Weber, K. ; Woolf, A. D. ; Wieland, E. ; Williams, R. ; Woolf, A. D. ; Ziegler, R. / Influence of physical activity on vertebral deformity in men and women : Results from the European Vertebral Osteoporosis Study. In: Journal of Bone and Mineral Research. 1997 ; Vol. 12, No. 5. pp. 813-819.
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title = "Influence of physical activity on vertebral deformity in men and women: Results from the European Vertebral Osteoporosis Study",
abstract = "Physical activity is associated with an increased bone mass and a reduced risk of hip fracture. There are, however, no data from population samples of men and women concerning the effect of regular levels of physical activity on the risk of vertebral deformity. The aim of this study was to determine the relationship between regular physical activity and vertebral deformity in European men and women. A population survey method was used. Thirty-six centers from 19 European countries participated. Each center recruited a population sample of men and women aged 50 years and over. Those who took part received an interviewer-administered questionnaire and lateral thoracolumbar radiographs. Subjects were asked about two dimensions of physical activity: (1) the level of physical activity undertaken either at work or at home on a daily basis at three different age periods: 15-25 years, 25-50 years, and 50+ years; and (2) the amount of time spent walking or cycling out of doors each day. Spinal radiographs were evaluated morphometrically and the presence of vertebral deformity was defined according to the McCloskey method. In total, 14,261 subjects, aged 50-79 years, from 30 centers were studied, of whom 809 (12.0{\%}) men and 884 (11.7{\%}) women had one or more deformities. After adjusting for age, center, smoking, and body mass index, very heavy levels of activity in all three age groups were associated with an increased risk of vertebral deformity in men (odds ratios, age adjusted [OR], 1.5-1.7; with all 95{\%} confidence intervals [CI] excluding unity). No increased risk was observed in women. Current walking or cycling more than 1/4 h/day was associated with a reduced risk of vertebral deformity in women (OR 0.8; 95{\%} CI 0.7-1.0). We conclude that regular walking in middle-aged and elderly women is associated with a reduced risk of vertebral deformity. By contrast, heavy levels of physical activity in early and middle adult life are associated with an increased risk in men. These differences are of relevance in understanding the epidemiology of vertebral deformity and planning programs of prevention.",
author = "Silman, {Alan J.} and O'Neill, {T. W.} and C. Cooper and J. Kanis and D. Felsenberg and K. Abendroth and D. Agnusdei and A. Antoniou and A. Aroso and D. Banzer and Benevolenskaya, {L. I.} and K. Bergmann and Bhalla, {A. K.} and Andia, {J. B Cannata} and S. Czekalski and Delmas, {P. D.} and J. Dequeker and {Diaz Curiel}, M. and {Diaz Lopez}, {J. B.} and G. Dilsen and R. Eastell and Falch, {J. A.} and B. Felsch and J. Franke and C. Gennari and P. Geusens and S. Havelka and A. Hofman and K. Hoszowski and I. Jajic and J. Janott and O. Johnell and L. Kalidis and S. Kirschner and C. Kiss and G. Krusekemper and T. Lauermann and A. Letkovska and Vaz, {A. Lopez} and Lorenc, {R. S.} and G. Lyritis and F. Marchand and D. Marsden and P. Masaryk and C. Matthis and J. Mews and Meyer, {H. E.} and T. Miazgowski and Mikhailov, {E. E.} and Diaz, {M. Naves} and B. Nilsson and S. Ortoloni and G. Petta and Pols, {H. A P} and G. Po{\'o}r and A. Rapado and P. Raptou and H. Raspe and J. Reeve and Reid, {D. M.} and W. Reisinger and F. Ring and Escofet, {D. Roig} and Martin, {M. Ruiz} and H. Schatz and C. Sheidt-Nave and M. Sosa and C. Todd and P. Vavrincova and J. Varlow and K. Weber and Woolf, {A. D.} and E. Wieland and R. Williams and Woolf, {A. D.} and R. Ziegler",
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TY - JOUR

T1 - Influence of physical activity on vertebral deformity in men and women

T2 - Results from the European Vertebral Osteoporosis Study

AU - Silman, Alan J.

AU - O'Neill, T. W.

AU - Cooper, C.

AU - Kanis, J.

AU - Felsenberg, D.

AU - Abendroth, K.

AU - Agnusdei, D.

AU - Antoniou, A.

AU - Aroso, A.

AU - Banzer, D.

AU - Benevolenskaya, L. I.

AU - Bergmann, K.

AU - Bhalla, A. K.

AU - Andia, J. B Cannata

AU - Czekalski, S.

AU - Delmas, P. D.

AU - Dequeker, J.

AU - Diaz Curiel, M.

AU - Diaz Lopez, J. B.

AU - Dilsen, G.

AU - Eastell, R.

AU - Falch, J. A.

AU - Felsch, B.

AU - Franke, J.

AU - Gennari, C.

AU - Geusens, P.

AU - Havelka, S.

AU - Hofman, A.

AU - Hoszowski, K.

AU - Jajic, I.

AU - Janott, J.

AU - Johnell, O.

AU - Kalidis, L.

AU - Kirschner, S.

AU - Kiss, C.

AU - Krusekemper, G.

AU - Lauermann, T.

AU - Letkovska, A.

AU - Vaz, A. Lopez

AU - Lorenc, R. S.

AU - Lyritis, G.

AU - Marchand, F.

AU - Marsden, D.

AU - Masaryk, P.

AU - Matthis, C.

AU - Mews, J.

AU - Meyer, H. E.

AU - Miazgowski, T.

AU - Mikhailov, E. E.

AU - Diaz, M. Naves

AU - Nilsson, B.

AU - Ortoloni, S.

AU - Petta, G.

AU - Pols, H. A P

AU - Poór, G.

AU - Rapado, A.

AU - Raptou, P.

AU - Raspe, H.

AU - Reeve, J.

AU - Reid, D. M.

AU - Reisinger, W.

AU - Ring, F.

AU - Escofet, D. Roig

AU - Martin, M. Ruiz

AU - Schatz, H.

AU - Sheidt-Nave, C.

AU - Sosa, M.

AU - Todd, C.

AU - Vavrincova, P.

AU - Varlow, J.

AU - Weber, K.

AU - Woolf, A. D.

AU - Wieland, E.

AU - Williams, R.

AU - Woolf, A. D.

AU - Ziegler, R.

PY - 1997

Y1 - 1997

N2 - Physical activity is associated with an increased bone mass and a reduced risk of hip fracture. There are, however, no data from population samples of men and women concerning the effect of regular levels of physical activity on the risk of vertebral deformity. The aim of this study was to determine the relationship between regular physical activity and vertebral deformity in European men and women. A population survey method was used. Thirty-six centers from 19 European countries participated. Each center recruited a population sample of men and women aged 50 years and over. Those who took part received an interviewer-administered questionnaire and lateral thoracolumbar radiographs. Subjects were asked about two dimensions of physical activity: (1) the level of physical activity undertaken either at work or at home on a daily basis at three different age periods: 15-25 years, 25-50 years, and 50+ years; and (2) the amount of time spent walking or cycling out of doors each day. Spinal radiographs were evaluated morphometrically and the presence of vertebral deformity was defined according to the McCloskey method. In total, 14,261 subjects, aged 50-79 years, from 30 centers were studied, of whom 809 (12.0%) men and 884 (11.7%) women had one or more deformities. After adjusting for age, center, smoking, and body mass index, very heavy levels of activity in all three age groups were associated with an increased risk of vertebral deformity in men (odds ratios, age adjusted [OR], 1.5-1.7; with all 95% confidence intervals [CI] excluding unity). No increased risk was observed in women. Current walking or cycling more than 1/4 h/day was associated with a reduced risk of vertebral deformity in women (OR 0.8; 95% CI 0.7-1.0). We conclude that regular walking in middle-aged and elderly women is associated with a reduced risk of vertebral deformity. By contrast, heavy levels of physical activity in early and middle adult life are associated with an increased risk in men. These differences are of relevance in understanding the epidemiology of vertebral deformity and planning programs of prevention.

AB - Physical activity is associated with an increased bone mass and a reduced risk of hip fracture. There are, however, no data from population samples of men and women concerning the effect of regular levels of physical activity on the risk of vertebral deformity. The aim of this study was to determine the relationship between regular physical activity and vertebral deformity in European men and women. A population survey method was used. Thirty-six centers from 19 European countries participated. Each center recruited a population sample of men and women aged 50 years and over. Those who took part received an interviewer-administered questionnaire and lateral thoracolumbar radiographs. Subjects were asked about two dimensions of physical activity: (1) the level of physical activity undertaken either at work or at home on a daily basis at three different age periods: 15-25 years, 25-50 years, and 50+ years; and (2) the amount of time spent walking or cycling out of doors each day. Spinal radiographs were evaluated morphometrically and the presence of vertebral deformity was defined according to the McCloskey method. In total, 14,261 subjects, aged 50-79 years, from 30 centers were studied, of whom 809 (12.0%) men and 884 (11.7%) women had one or more deformities. After adjusting for age, center, smoking, and body mass index, very heavy levels of activity in all three age groups were associated with an increased risk of vertebral deformity in men (odds ratios, age adjusted [OR], 1.5-1.7; with all 95% confidence intervals [CI] excluding unity). No increased risk was observed in women. Current walking or cycling more than 1/4 h/day was associated with a reduced risk of vertebral deformity in women (OR 0.8; 95% CI 0.7-1.0). We conclude that regular walking in middle-aged and elderly women is associated with a reduced risk of vertebral deformity. By contrast, heavy levels of physical activity in early and middle adult life are associated with an increased risk in men. These differences are of relevance in understanding the epidemiology of vertebral deformity and planning programs of prevention.

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