Influence of membrane fluidity changes upon the imprinting of polypeptide hormones in Tetrahymena

Péter Kovács, György Csaba, Yoshinori Nozawa

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

1. 1. Hormonal imprinting is a physiological phenomenon, in which after the first encounter the receptorial and functional responses of a cell change for future occasions. 2. 2. The present experiments demonstrate (using Tetrahymena as a model cell) that the imprinting is very sensitive to the changes in membrane physical state. 3. 3. Cultivation of Tetrahymena cells in 28 or 15°C or in ergosterol-supplemented media caused only quantitative differences in the imprinting; however, the process of cooling (shift-down) or reheating (shift-up) resulted in a false reaction. 4. 4. The combined treatment by ergosterol and cooling completely abolished the imprinting. 5. 5. These results indicate that hormonal imprinting is a membrane-dependent process.

Original languageEnglish
Pages (from-to)763-766
Number of pages4
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume78
Issue number4
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Physiology

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