Influence of HgCl2 on the osphradial multisensory system of Lymnaea stagnalis L.

N. N. Kamardin, A. Szűcs, Katalin S-Rózsa

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The osphradial multisensory system of Lymnaea stagnalis L. (Pulmonata, Basommatophora) was used to demonstrate the modulation of chemosensory information both at periphery and central nervous system (CNS) following heavy metal treatments. A semi-intact preparation including osphradium, CNS and the right inner parietal nerve (r.i.p.n.) connecting them was used to record both extracellular activity of nerve and intracellular activity of central neurons receiving information from osphradium. The ion currents of osphradium were recorded using patch, clamp method. The changes in nerve and neuronal activity were expressed by averaging of firing frequency and interspike intervals. The chemosensory function of osphradium was shown by application of L-aspartate, urea, saccharose and stagnant water to its surface. The central neurons reacting to the stimulation of osphradium were located to visceral, right parietal, pedal and cerebral ganglia of Lymnaea. Both the acute and chronic treatments with HgCl2 damaged the sensory function of osphradium traced on the flow of information from periphery to central neurons. At the same thee, mercury chloride modified the synaptic connections of respiratory pattern generators as well as the Ca- and K-dependent ion currents of osphradial neurons. The results proved the multisensory role of osphradium sensing the alterations in the environment and its usefulness in monitoring the effects of pollutants at various level of regulation from chemosensory epithelium to CNS.

Original languageEnglish
Pages (from-to)99-116
Number of pages18
JournalActa Biologica Hungarica
Volume50
Issue number1-3
Publication statusPublished - 1999

Fingerprint

Lymnaea
Mercuric Chloride
nervous system
Neurons
Neurology
Central Nervous System
ion
Ions
urea
Clamping devices
Heavy Metals
Mercury
chloride
Aspartic Acid
Ganglia
heavy metal
Sucrose
Urea
Foot
Chlorides

Keywords

  • CNS
  • HgCl
  • Ion currents
  • Osphradium
  • Spike frequency analysis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

Cite this

Influence of HgCl2 on the osphradial multisensory system of Lymnaea stagnalis L. / Kamardin, N. N.; Szűcs, A.; S-Rózsa, Katalin.

In: Acta Biologica Hungarica, Vol. 50, No. 1-3, 1999, p. 99-116.

Research output: Contribution to journalArticle

Kamardin, N. N. ; Szűcs, A. ; S-Rózsa, Katalin. / Influence of HgCl2 on the osphradial multisensory system of Lymnaea stagnalis L. In: Acta Biologica Hungarica. 1999 ; Vol. 50, No. 1-3. pp. 99-116.
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