Infectious bronchitis of chicken is a well known disease since the beginning of the 1900's, but has remained a continuous challenge for both the broiler and layer industry. Besides the respiratory signs, the affected flocks often suffer from kidney damage or egg-production problems. During the recent years, several infectious bronchitis strains or closely related coronaviruses have been isolated from gailinaceus and non-gallinaceus species, which might be indicative of replication of these viruses in species apart from their original host. Antigenic differences between the strains are in connection with the variance of the amino-acid order of S1 protein. Although, these differences not always reflect the real relationship between the immunity and genotype of the strains. Therefore, we always have to be careful to choose and properly evaluate the diagnostic methods and their results. The numerous different serotypes and their high variability necessitate regular monitoring of the flocks and continuous development of vaccines. Live and inactivated vaccines have been used for a long time in the affected flocks worldwide. Although, the absence of cross-protection between serotypes or the inadequate application often result in deficient immune response. Several so called "new generation" vaccines have been developed in the recent years to assure a more reliable and safer protection in chickens. One of them, which can be administered in ovo, might have a great opportunity to develop an early and homologue immunity in the flocks.
|Translated title of the contribution||Infectious bronchitis of chickens. Literature review|
|Number of pages||9|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Apr 30 2009|
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