Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain

Atsushi Asanuma, Tetsuro Horikoshi, Keiji Yanagisawa, Kaijiro Anzai, S. Goto, Tohru Yoshioka

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A taurine response was induced in the surface membrane of the oocytes of Xenopus laevis by injection of the mRNA from the neonatal mouse brain, and the response was studied electrophysiologically. The permeability of mRNA-injected oocytes to chloride ions was increased by the application of taurine in a dose-dependent manner. The same oocyte also responded to GABA, but bicuculline suppressed only the GABA response. These results suggest a possibility that taurine could be a neurotransmitter of certain neurons as yet unknown in the central nervous system.

Original languageEnglish
Pages (from-to)249-253
Number of pages5
JournalNeuroscience Letters
Volume69
Issue number3
Publication statusPublished - Sep 12 1986

Fingerprint

Taurine
Xenopus
Oocytes
gamma-Aminobutyric Acid
Messenger RNA
Brain
Bicuculline
Xenopus laevis
Neurotransmitter Agents
Chlorides
Permeability
Central Nervous System
Ions
Neurons
Injections
Membranes

Keywords

  • γ-Aminobutyric acid
  • Bicuculline
  • Mouse brain
  • mRNA
  • Oocyte
  • Receptor
  • Taurine

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Asanuma, A., Horikoshi, T., Yanagisawa, K., Anzai, K., Goto, S., & Yoshioka, T. (1986). Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain. Neuroscience Letters, 69(3), 249-253.

Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain. / Asanuma, Atsushi; Horikoshi, Tetsuro; Yanagisawa, Keiji; Anzai, Kaijiro; Goto, S.; Yoshioka, Tohru.

In: Neuroscience Letters, Vol. 69, No. 3, 12.09.1986, p. 249-253.

Research output: Contribution to journalArticle

Asanuma, A, Horikoshi, T, Yanagisawa, K, Anzai, K, Goto, S & Yoshioka, T 1986, 'Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain', Neuroscience Letters, vol. 69, no. 3, pp. 249-253.
Asanuma A, Horikoshi T, Yanagisawa K, Anzai K, Goto S, Yoshioka T. Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain. Neuroscience Letters. 1986 Sep 12;69(3):249-253.
Asanuma, Atsushi ; Horikoshi, Tetsuro ; Yanagisawa, Keiji ; Anzai, Kaijiro ; Goto, S. ; Yoshioka, Tohru. / Induction of taurine responsiveness in Xenopus oocytes by messenger RNA from mouse brain. In: Neuroscience Letters. 1986 ; Vol. 69, No. 3. pp. 249-253.
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