Induction of melatonin synthesis in Tetrahymena pyriformis by hormonal imprinting--a unicellular "factory" of the indoleamine.

L. Köhidai, O. Vakkuri, M. Keresztesi, J. Leppäluoto, G. Csaba

Research output: Contribution to journalArticle

16 Citations (Scopus)


Melatonin is present in Tetrahymena and its synthesis can be enhanced by pretreatment (imprinting) with melatonin. Two days after imprinting melatonin level is elevated in the cells and more elevated in the supematant. Such a minute quantity, as 10(-12) M melatonin for 1 hour is able to provoke imprinting, however the effect is more expressed using 10(-6) M. Maintenance in light conditions further elevated the amount of melatonin in the cells and supematant alike, related to the melatonin content of cells kept in darkness. The experiments call attention to the light-sensitivity of imprinting-provoked melatonin production in Tetrahymena and to the possibility of using this property for important physiological functions in higher grades of phylogeny.

Original languageEnglish
Pages (from-to)521-524
Number of pages4
JournalCellular and molecular biology (Noisy-le-Grand, France)
Issue number4
Publication statusPublished - Jun 2003


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this