The authors summarize the knowledge about the recently discovered mechanism of induced ovulation in Camelids and compare it to the well established 'classical' model of spontaneous and induced ovulation. In the eighties, Chinese authors (19) demonstrated that a so-called Ovulation Induction Factor (OIF) found in the seminal plasma of male Bactrian camels causes ovulation in females. Some 20 years later, Canadian scientists isolated and identified this ovulation inducing factor (OIF) from alpaca and llama semen. Recently, they have discovered simultaneously with researchers from Australia that OIF is identical to a well known neurotrophic the so-called beta-neuro growth factor (beta-NGF syn. β-NGF). According to the current hypothesis, β-NGF is absorbed from the uterus following copulation, reaches the central nervous system through blood transport, and by acting on the hypothalamus and/ or hypophysis β-NGF induces the preovulatory LH surge. This new model of induced ovulation in Camelids differs from the previously described, classical model of induced ovulation. Remarkably, the presence of β-NGF was also demonstrated in the seminal plasma of spontaneous ovulator species (boars and bulls), moreover the biological activity of the molecule present in their semen is preserved.
|Translated title of the contribution||Induced ovlation in Camelids: The role of beta-nerve growth factor. Literature review|
|Number of pages||9|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Jul 2014|
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