Independent validation of Parkinson'S disease Sleep Scale 2nd version (PDSS-2)

N. Kovács, Krisztina Horváth, Zsuzsanna Aschermann, Péter Ács, Edit Bosnyák, Gabriella Deli, Endre Pál, J. Janszky, Béla Faludi, Kázmér Karádi, Ildikó Késmárki, Magdolna Bokor, Eszter Rigó, Júlia Lajtos, P. Klivényi, G. Dibó, L. Vécsei, Annamária Takáts, Adrián Tóth, Piroska Imre & 5 others Ferenc Nagy, Mihály Herceg, A. Kamondi, Eszter Hidasi, S. Komoly

Research output: Contribution to journalArticle

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Abstract

Sleep problems are one of the most common non-motor symptoms of Parkinson's disease (PD). The Parkinson's disease Sleep Scale 2nd version (PDSS-2) was published in 2011 showing satisfactory clinimetric results. We performed an independent testing of the scale adding further information on its clinimetric properties. In this nationwide study 537 PD patients were enrolled. Besides PDSS-2, we assessed Patient's Global Impression-Severity (PGI) scale on sleep disturbances, Non-motor Symptoms Scale and MDS-UPDRS. Following the Classical Theory of Tests we performed descriptive data analysis, factor analysis, reliability, validity and precision measurements. Subsequently, we evaluated cut-off value for detecting clinically meaningful sleep problems based on receiver operating characteristics analysis. Based on the PGI scale, 161 patients (30.0 %) did not reported any sleep problems. Factor analysis revealed almost the same factor structure described by the original PDSS-2 validation study. Cronbach's alpha was 0.863 and all item had good itemtotal correlation. PDSS-2 demonstrated high convergent validity with Non-Motor Symptoms Scale and Clinical Global Impression-Severity and non-motor part of MDSUPDRS, and divergent validity with age, gender, education level, disease-duration and Hoehn-Yahr Stages. Presence of sleep problems was identified by scores[10.5 points on PDSS-2 (sensitivity 85.3 %, specificity 60.8 %, diagnostic accuracy 78.1 %); whereas scores[19.5 points indicated marked sleep-related problems (specificity 68.5 %, sensitivity 78.0 %, diagnostic accuracy 74.3 %). Independent and cross-cultural validation of patient reported outcomes is essential to confirm or reject the findings obtained by the developers of the scale. Our results demonstrate that fundamental clinimetric properties of the PDSS-2 are satisfactory.

Original languageEnglish
Pages (from-to)63-73
Number of pages11
JournalSleep and Biological Rhythms
Volume14
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Parkinson Disease
Sleep
Statistical Factor Analysis
Sensitivity and Specificity
Validation Studies
Reproducibility of Results
ROC Curve
Education

Keywords

  • Precision
  • Receiver operating characteristic
  • Reliability
  • Sleep
  • Validity

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)
  • Neurology
  • Neuropsychology and Physiological Psychology

Cite this

Independent validation of Parkinson'S disease Sleep Scale 2nd version (PDSS-2). / Kovács, N.; Horváth, Krisztina; Aschermann, Zsuzsanna; Ács, Péter; Bosnyák, Edit; Deli, Gabriella; Pál, Endre; Janszky, J.; Faludi, Béla; Karádi, Kázmér; Késmárki, Ildikó; Bokor, Magdolna; Rigó, Eszter; Lajtos, Júlia; Klivényi, P.; Dibó, G.; Vécsei, L.; Takáts, Annamária; Tóth, Adrián; Imre, Piroska; Nagy, Ferenc; Herceg, Mihály; Kamondi, A.; Hidasi, Eszter; Komoly, S.

In: Sleep and Biological Rhythms, Vol. 14, No. 1, 01.01.2016, p. 63-73.

Research output: Contribution to journalArticle

Kovács, N, Horváth, K, Aschermann, Z, Ács, P, Bosnyák, E, Deli, G, Pál, E, Janszky, J, Faludi, B, Karádi, K, Késmárki, I, Bokor, M, Rigó, E, Lajtos, J, Klivényi, P, Dibó, G, Vécsei, L, Takáts, A, Tóth, A, Imre, P, Nagy, F, Herceg, M, Kamondi, A, Hidasi, E & Komoly, S 2016, 'Independent validation of Parkinson'S disease Sleep Scale 2nd version (PDSS-2)', Sleep and Biological Rhythms, vol. 14, no. 1, pp. 63-73. https://doi.org/10.1007/s41105-015-0024-8
Kovács, N. ; Horváth, Krisztina ; Aschermann, Zsuzsanna ; Ács, Péter ; Bosnyák, Edit ; Deli, Gabriella ; Pál, Endre ; Janszky, J. ; Faludi, Béla ; Karádi, Kázmér ; Késmárki, Ildikó ; Bokor, Magdolna ; Rigó, Eszter ; Lajtos, Júlia ; Klivényi, P. ; Dibó, G. ; Vécsei, L. ; Takáts, Annamária ; Tóth, Adrián ; Imre, Piroska ; Nagy, Ferenc ; Herceg, Mihály ; Kamondi, A. ; Hidasi, Eszter ; Komoly, S. / Independent validation of Parkinson'S disease Sleep Scale 2nd version (PDSS-2). In: Sleep and Biological Rhythms. 2016 ; Vol. 14, No. 1. pp. 63-73.
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AU - Bosnyák, Edit

AU - Deli, Gabriella

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AU - Janszky, J.

AU - Faludi, Béla

AU - Karádi, Kázmér

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AU - Bokor, Magdolna

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