Diurnal changes in plasma corticosterone and hypothalamic serotonin content were investigated in normal male rats and in animals in which the anterior connections of the medial basal hypothalamus were interrupted. While in normal animals there is an inverse time-relationship between the rhythmicity of plasma corticosterone and hypothalamic serotonin content, frontal isolation of the medial basal hypothalamus eliminates only the plasma corticosterone rhythm without affecting the hypothalamic serotonin content rhythm. It seems probable that hypothalamic serotoninergic terminals do not participate in the regulation of diurnal secretion of adrenocorticotropin hormone.
|Number of pages||6|
|Publication status||Published - Dec 1 1980|
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