Increased technetium-99m-HMPAO uptake in grade II astrocytoma

F. Grunwald, C. Menzel, T. Pietsch, L. Pavics, A. Hufnagel, H. J. Biersack

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5 Citations (Scopus)


Most brain tumors show decreased uptake of blood flow tracers in brain SPECT imaging and in some cases meningiomas show increased uptake, mainly associated with high regional blood flow values (1-14). A reason for regionally increased tracer uptake is partial epilepsy when a tracer is injected during the ictal phase (15-17). We present a case of a histologically proven Grade II astrocytoma in the mesial part of the left temporal lobe that caused complex partial seizures. After tracer injection during a phase without signs of clinical seizure, markedly increased uptake of 99mTc-hexamethylpropyleneamine oxime 99mTc-HM-PAO) occurred, although the tumor was partially calcified.

Original languageEnglish
Pages (from-to)804-806
Number of pages3
JournalJournal of Nuclear Medicine
Issue number5
Publication statusPublished - Jan 1 1995


  • astrocytoma
  • epilepsy
  • magnetic resonance imaging
  • single-photon emission computer tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Grunwald, F., Menzel, C., Pietsch, T., Pavics, L., Hufnagel, A., & Biersack, H. J. (1995). Increased technetium-99m-HMPAO uptake in grade II astrocytoma. Journal of Nuclear Medicine, 36(5), 804-806.