Increased tear osmolarity in patients with severe cases of conjunctivochalasis

Eszter Fodor, Krisztina Kosina-Hagy, Mria Bausz, Jnos Németh

Research output: Contribution to journalArticle

13 Citations (Scopus)


Purpose: To evaluate and compare tear osmolarity in different grades of conjunctivochalasis. Patients and methods: Forty subjects divided into four groups based on grading of conjunctivochalasis by lid-paralell conjunctival fold (LIPCOF) test and tear osmolarity evaluated by TearLab osmometer. Schirmer test, tear film break up time (BUT) and vital staining were also performed. Results: Patients with mild and moderate conjunctivochalasis showed similar tear osmolarity to normal subjects. A significant increase (P<0.008) of osmolarity was found in patients with severe conjunctivochalasis. A significant increase of osmolarity was found in patients with abnormal BUT (P=0.018) and in patients with positive lissamine-green staining (P=0.023). No association could be elicited when results of osmolarity were compared to those of Schirmer test or when compared those of fluorescein staining to osmolarity, respectively. Conclusion: Hyperosmolarity of tear was reported as a fact of ocular surface inflammation. While in mild and moderate conjunctivochalasis tear osmolarity was similar to normal controls, increased osmolarity can refer to the presence of ocular surface inflammation in these patients with severe conjunctivochalasis.

Original languageEnglish
Pages (from-to)80-84
Number of pages5
JournalCurrent Eye Research
Issue number1
Publication statusPublished - Jan 1 2012


  • Conjunctivochalasis
  • Inflammation
  • Tear osmolarity
  • TearLab osmometer

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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